Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy. Large vessel occlusion (LVO) accounts for up to 38% of acute ischaemic stroke and comes with devastating outcomes for patients, families and society in the pre-intervention era. A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke; this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits. This review article will present a comprehensive overview of LVO management, techniques and devices used, and the future of stroke therapy. In addition, we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion.
- large vessel occlusion
- mechanical thrombectomy
- functional outcome
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Contributors All authors reviewed and agreed on the final version of the manuscript. Conception or design of the work: AS, BH, SR, JHW, PJ. Drafting the work: AS, BH, SR, DW, TDA, MD, JD, DJ-MM. Revising the work for valuable intellectual content: MRG, HZ, VR, DMH, RHR. Final approval of the version: ST, PJ.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests PJ is a consultant for Medtronic and Micro Vention. ST is a consultant for Stryker.
Patient consent for publication Not required.
Provenance and peer review Commissioned; internally peer reviewed.
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