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BMJ Journals

Online First

October 04, 2024

Original research
Bone marrow-derived mesenchymal stem cell ameliorates post-stroke enterobacterial translocation through liver-gut axis

Xiaotao Su, Tiemei Li, Yuge Wang, Lei Wei, Banghao Jian, Xinmei Kang, Mengyan Hu, Chunyi Li, Shisi Wang, Danli Lu, Shishi Shen, Huipeng Huang, Yuxin Liu, Xiaohui Deng, Bingjun Zhang, Wei Cai, Zhengqi Lu

doi: 10.1136/svn-2024-003494

October 02, 2024

Original research
Extracellular vesicles bearing serum amyloid A1 exacerbate neuroinflammation after intracerebral haemorrhage

Huimin Zhu, Ningning Wang, Yingying Chang, Ying Zhang, Shihe Jiang, Xiaoping Ren, Meng Yuan, Haoxiao Chang, Wei-Na Jin

doi: 10.1136/svn-2024-003525
Short report
Definitions of white matter hyperintensity change: impact on estimates of progression and regression

Angela C C Jochems, Susana Muñoz Maniega, Una Clancy, Carmen Arteaga Reyes, Daniela Jaime Garcia, Maria del C. Valdés Hernández, Francesca M Chappell, Gayle Barclay, Charlotte Jardine, Donna McIntyre, Iona Gerrish, Stewart Wiseman, Michael S Stringer, Michael J Thrippleton, Fergus Doubal, Joanna M Wardlaw

doi: 10.1136/svn-2024-003300
Protocol
Advance Consent for participation in Acute Stroke Trials (ACTION): protocol for a feasibility study

Ubong Udoh, Rena Seeger, Brian Dewar, Emma Cummings, Sophia Gocan, Stuart Nicholls, Mark Fedyk, Victoria Shepherd, Jeff Perry, Robert Fahed, Tim Ramsay, Jamie Brehaut, Michael D Hill, Alexandre Y Poppe, Bijoy K Menon, Richard H Swartz, Dar Dowlatshahi, Michel Shamy

doi: 10.1136/svn-2023-003029
Protocol
Intra-arterial tenecteplase after successful endovascular therapy (ANGEL-TNK): protocol of a multicentre, open-label, blinded end-point, prospective, randomised trial

Xiaochuan Huo, Gang Luo, Dapeng Sun, Thanh Nguyen, Mohamad Abdalkader, Wenhuo Chen, Xiaoxi Yao, Guangxiong Yuan, Tingyu Yi, Hongxin Han, Yuesong Pan, Tudor G Jovin, David S Liebeskind, Liping Liu, Xingquan Zhao, Zeguang Ren, Yilong Wang, Yongjun Wang, Bernard Yan, Zhongrong Miao

doi: 10.1136/svn-2024-003318
Original research
Exosomes-mediated delivery of miR-486-3p alleviates neuroinflammation via SIRT2-mediated inhibition of mitophagy after subarachnoid hemorrhage

Bin Sheng, Sen Gao, XiangXin Chen, Yang Liu, Niansheng Lai, Jin Dong, Jiaqing Sun, Yan Zhou, Lingyun Wu, Chun-Hua Hang, Wei Li

doi: 10.1136/svn-2024-003509

September 28, 2024

Review
Central post-stroke pain: advances in clinical and preclinical research

Xiqian Yuan, Siyuan Hu, Xiaochong Fan, Chao Jiang, Yan Xu, Ruochen Hao, Zili Xu, Yiyang Yu, Yousef Rastegar-Kashkooli, Leo Huang, Tom J Wang, Qiao Wang, Songxue Su, Limin Wang, Junyang Wang, Menglu Wang, Yun Tai Kim, Ujjal K Bhawal, Fushun Wang, Ting Zhao, Junmin Wang, Xuemei Chen, Jian Wang

doi: 10.1136/svn-2024-003418
Protocol
Angioplasty and/or stenting following successful mechanical thrombectomy for intracranial atherosclerosis-related emergent large vessel occlusive stroke (ASSET): protocol of a multicentre randomised trial

Geng Liao, Hongyu Qiao, Chengbo Dai, Weiwen Yi, Liang Zhang, Zai Liang, Li Li, Yuemei He, Zhenyu Zhang, Zhong Ji, Li’an Huang

doi: 10.1136/svn-2024-003435

September 17, 2024

Original research
Association between stroke subtypes and outcomes of endovascular therapy: a post-hoc analysis of the ANGEL-ASPECT Trial

Da Lu, Raynald , Dapeng Sun, Na Zheng, Bohao Zhang, Leilei Luo, Sifei Wang, Sihu Pan, Yuchao Dou, Mengxing Wang, Yuesong Pan, Xiaochuan Huo, Zhongrong Miao, Ming Wei

doi: 10.1136/svn-2024-003115

September 13, 2024

Original research
Predictors of malignant swelling in space-occupying cerebellar infarction

Enayatullah Baki, Lea Baumgart, Victoria Kehl, Felix Hess, Andreas Wolfgang Wolff, Arthur Wagner, Moritz Roman Hernandez Petzsche, Tobias Boeckh-Behrens, Bernhard Hemmer, Bernhard Meyer, Jens Gempt, Silke Wunderlich

doi: 10.1136/svn-2024-003360
Original research
Optimal duration of dual antiplatelet therapy for minor stroke within 72 hours of symptom onset: a prospective cohort study

Tingting Liu, Yongle Wang, Kaili Zhang, Haimei Fan, Yanan Li, Jing Ren, Juan Li, Yali Li, Xinyi Li, Wu Xuemei, Junhui Wang, Lixi Xue, Xiaolei Gao, Yuping Yan, Gaimei Li, Qingping Liu, Wenhua Niu, Wenxian Du, Yuting Liu, Xiaoyuan Niu

doi: 10.1136/svn-2023-002933

September 11, 2024

Short report
Sex differences in the epidemiology of spontaneous and traumatic cervical artery dissections

Elke Schipani, Kim J Griffin, Carlee I Oakley, Zafer Keser

doi: 10.1136/svn-2024-003282
Original research
miR-19-3p/GRSF1/COX1 axis attenuates early brain injury via maintaining mitochondrial function after subarachnoid haemorrhage

Ge Gao, Xiaoyu Sun, Jiajia Xu, Jian Yu, Yang Wang

doi: 10.1136/svn-2024-003099
Original research
Asymptomatic carotid artery stenosis is associated with increased Alzheimer’s disease and non-Alzheimer’s disease dementia risk

Francesca Vitali, Georgina Torrandell-Haro, Gregory Branigan, Juan Arias Aristizabal, Eric Reiman, Edward J Bedrick, Roberta Diaz Brinton, Craig Weinkauf

doi: 10.1136/svn-2024-003164
Pictures of stroke and cerebral vasculature
Pictures of stroke and cerebral vasculature: novel insights and detailed visualisation of U-shaped elastin distribution and disorganised fibre arrangement at carotid bifurcations by advanced techniques

Shen Li, Peipei Li, Xin Wang, Zongping Xia, Yuming Xu

doi: 10.1136/svn-2024-003528
Original research
Association between ASPECTS region of infarction and clinical outcome in non-acute large vessel occlusion ischaemic stroke after endovascular recanalisation

Jialiang Lu, Ziwei Lu, Ye Li, Fangcun Li, Yuxuan Feng, Meijuan Dang, Yang Yang, Fan Tang, Tao Li, Lili Zhao, Yating Jian, Xiaoya Wang, Lei Zhang, Hong Fan, Guilian Zhang

doi: 10.1136/svn-2024-003355

August 28, 2024

Perspective
Why non-human primates are needed in stroke preclinical research

Xiya Long, Jinsheng Zeng

doi: 10.1136/svn-2024-003504

August 24, 2024

Original research
PRCP is a promising drug target for intracranial aneurysm rupture supported via multi-omics analysis

Jinghao Wu, Yunyun Mei, XinYu Li, Wen-Kai Yu, Zi Han Zhou, Yinghao Yang, Pengpeng Niu, Yunchao Wang, Chang-He Shi, Hanghang Zhu, Wenjun He, Yuan Gao, Yuming Xu, Yusheng Li

doi: 10.1136/svn-2023-003076

August 21, 2024

Systematic review
Percutaneous transluminal angioplasty and stenting (PTAS) in patients with symptomatic intracranial vertebrobasilar artery stenosis (IVBS)

Ramtin Pourahmad, Kiarash Saleki, Sina Zoghi, Ramtin Hajibeygi, Hamed Ghorani, Amin Javanbakht, Sina Goodarzi, Parsa Alijanizadeh, Kelly Trinh, Ravi Shastri, Mohammad Ghasemi-Rad

doi: 10.1136/svn-2024-003224
Systematic review
Antiplatelet therapy versus intravenous thrombolysis for mild acute ischaemic stroke: a living systematic review and meta-analysis

Mingzhen Qin, Tingting Liu, Xinyi Shi, Luda Feng, Tingting Li, Zixin Cheng, Sisong Cheng, Congren Zhou, Mingrun Zou, Qi Jia, Chi Zhang, Ying Gao

doi: 10.1136/svn-2024-003097

August 20, 2024

Original research
Magnitude of systolic blood pressure reduction following endovascular treatment and clinical outcomes in acute large artery occlusion stroke

Xianjun Huang, Xianhui Ding, Hao Wang, Qiankun Cai, Junfeng Xu, Zibao Li, Qian Yang, Zhiming Zhou, Jie Xu

doi: 10.1136/svn-2024-003221

August 19, 2024

Original research
Anaesthesia modality on endovascular therapy outcomes in patients with large infarcts: a post hoc analysis of the ANGEL-ASPECT trial

Fa Liang, Kangda Zhang, Youxuan Wu, Xinyan Wang, Xuan Hou, Yun Yu, Yunzhen Wang, Mengxing Wang, Yuesong Pan, Xiaochuan Huo, Ruquan Han, Zhongrong Miao

doi: 10.1136/svn-2024-003320
Original research
Obesity and brain volumes: mediation by cardiometabolic and inflammatory measures

Qi Zhou, Wanlin Zhu, Xueli Cai, Jing Jing, Mengxing Wang, Suying Wang, Aoming Jin, Xia Meng, Tiemin Wei, Yongjun Wang, Yuesong Pan

doi: 10.1136/svn-2023-003045

August 06, 2024

Original research
Safety and efficacy of GD-11 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Runhua Zhang, Gaifen Liu, Xingquan Zhao, Yilong Wang, Zixiao Li, Guofang Chen, Bo Liu, Yun Ling, Yongjun Wang, Shuya Li

doi: 10.1136/svn-2024-003338

August 03, 2024

Editorial
Should patients with minor strokes be given thrombolytics?

Xun Wang, Yi Dong, Qiang Dong, David Wang

doi: 10.1136/svn-2024-003451

July 23, 2024

Protocol
DRug-coated Balloon for Endovascular treatment of sYmptOmatic intracraNial stenotic Disease (DR. BEYOND): the protocol of a multicentre randomised trial

Dapeng Mo, Xu Tong, Xiaoqing Li, Chuan Qin, Yuesong Pan, Sheng Guan, Zhongrong Miao

doi: 10.1136/svn-2024-003259

July 05, 2024

Original research
Determinants of prehospital and in-hospital delay in patients with symptomatic carotid stenosis and their influence on the outcome after elective carotid endarterectomy

Felix Kirchhoff, Christoph Knappich, Michael Kallmayer, Bianca Bohmann, Vanessa Lohe, Pavlos Tsantilas, Shamsun Naher, Hans-Henning Eckstein, Andreas Kühnl

doi: 10.1136/svn-2024-003098

June 25, 2024

Original research
Healthy lifestyles are associated with alleviating the single-nucleotide polymorphism-based genetic risks of ischaemic stroke, intracerebral haemorrhage and myocardial infarction

Jingru Wang, Zhenqiu Liu, Chengxin Hu, Renjia Zhao, Dongliang Zhu, Yijing Xie, Pengyan Zhang, Mei Cui, Kelin Xu, Genming Zhao, Li Jin, Xingdong Chen, Chen Suo, Yanfeng Jiang

doi: 10.1136/svn-2024-003257

June 21, 2024

Original research
New rat model of spinal cord infarction with long-lasting functional disabilities generated by intraspinal injection of endothelin-1

Masayuki Otani, Yoshihiro Kushida, Yasumasa Kuroda, Shohei Wakao, Yo Oguma, Keisuke Sasaki, Shintaro Katahira, Ryohei Terai, Rie Ryoke, Hiroi Nonaka, Ryuta Kawashima, Yoshikatsu Saiki, Mari Dezawa

doi: 10.1136/svn-2023-002962

June 17, 2024

Original research
Impact of premorbid hypertension and renin-angiotensin-aldosterone system inhibitors on the severity of aneurysmal subarachnoid haemorrhage: a multicentre study

Ping Zhong, Zhiwen Lu, Zhangyu Li, Tianxiao Li, Qing Lan, Jianmin Liu, Sifang Chen, Zhanxiang Wang, Qinghai Huang

doi: 10.1136/svn-2023-003052

June 14, 2024

Protocol
Efficacy and safety of Ferrous iron on the prevention of Vascular cOgnitive impaiRment among patients with cerebral Infarction/TIA (FAVORITE): rationale and design of a multicentre randomised trial

Qian Jia, Peng Lei, Li Sun, Wei Li Jia, Yuesong Pan, Baoshi Yuan, Yinkai Wang, Qi Zhou, Xia Meng, Jing Jing, Jinxi Lin, Anxin Wang, Shuting Zhang, Zhen Hong, Yu Yang, Yunyun Xiong, Zixiao Li, Yilong Wang, Xingquan Zhao, Yongjun Wang

doi: 10.1136/svn-2023-002644
Short report
Intensity of statin therapy after ischaemic stroke and long-term outcomes: a nationwide cohort study

Ville Kytö, Julia Åivo, Jori O Ruuskanen

doi: 10.1136/svn-2024-003230

June 11, 2024

Original research
Left atrial appendage closure in patients with atrial fibrillation and acute ischaemic stroke despite anticoagulation

Avia Abramovitz Fouks, Shadi Yaghi, Magdy H Selim, Elif Gökçal, Alvin S Das, Ofer Rotschild, Scott B Silverman, Aneesh B Singhal, Sunil Kapur, Steven M Greenberg, Mahmut Edip Gurol

doi: 10.1136/svn-2024-003143

June 10, 2024

Original research
Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial

Yunyun Xiong, Liyuan Wang, Yuesong Pan, Mengxing Wang, Lee H Schwamm, Chunmiao Duan, Bruce C V Campbell, Shuya Li, Manjun Hao, Na Wu, Zhixin Cao, Shuangzhe Wu, Zixiao Li, Yongjun Wang

doi: 10.1136/svn-2023-003048

June 05, 2024

Original research
Paediatric intracranial dural arteriovenous fistulas: clinical characteristics, treatment outcomes and prognosis

Xin Su, Yongjie Ma, Zihao Song, Ming Ye, Hongqi Zhang, Peng Zhang

doi: 10.1136/svn-2024-003122

May 30, 2024

Original research
Left atrial appendage closure for patients with atrial fibrillation at high intracranial haemorrhagic risk

Avia Abramovitz Fouks, Shadi Yaghi, Elif Gokcal, Alvin S Das, Ofer Rotschild, Scott B Silverman, Aneesh B Singhal, Jorge Romero, Sunil Kapur, Steven M Greenberg, Mahmut Edip Gurol

doi: 10.1136/svn-2024-003142
Original research
Revascularisation patterns and characteristics after erythropoietin pretreatment and multiple burr holes in patients who had acute stroke with perfusion impairment

Seong-Joon Lee, So Young Park, Geun Hwa Park, Jin Soo Lee, Yong Cheol Lim, Ji Man Hong

doi: 10.1136/svn-2023-002831
Editorial
Patient-reported outcome measure and its application in patients with stroke: item response theory

Jia Ma, Jinma Ren, Joseph C Cappelleri

doi: 10.1136/svn-2024-003166

May 28, 2024

Systematic review
Clinical implications of haemodynamics in symptomatic intracranial atherosclerotic stenosis by computational fluid dynamics modelling: a systematic review

Yu Liu, Shuang Li, Haipeng Liu, Xuan Tian, Yuying Liu, Ziqi Li, Thomas W Leung, Xinyi Leng

doi: 10.1136/svn-2024-003202

May 23, 2024

Protocol
Role of histone deacetylases and sirtuins in the ischaemic stroke: a protocol for a systematic review and meta-analysis of animal studies

Ali Majdi, Hossein Mostafavi, Ali Moharrami, Shahin Yaraghi, Amirreza Ghaffari Tabrizi, Morteza Dojahani, Erfan Alirezapour, Kamyar Mansori

doi: 10.1136/svn-2024-003235
Original research
Exploring the relationship between embolic acute stroke distribution and supra-aortic vessel patency: key findings from an in vitro model study

Aglae Velasco Gonzalez, Cristina Sauerland, Dennis Görlich, Joaquin Ortega-Quintanilla, Astrid Jeibmann, Andreas Faldum, Werner Paulus, Walter Heindel, Boris Buerke

doi: 10.1136/svn-2023-003024
Systematic review
Cisternal and intraventricular irrigation in subarachnoid and intraventricular haemorrhage

Allice Nyborg Rosenkrans Lind, Mathias Green Krabbenhøft, Jan Brink Valentin, Mette Haldrup, Stig Dyrskog, Mads Rasmussen, Claus Ziegler Simonsen, Anders Rosendal Korshoej

doi: 10.1136/svn-2023-003062

May 21, 2024

Original research
Racial disparities in access to, and outcomes of, acute ischaemic stroke treatments in the USA

Luke Kiefer, David Daniel, Sai Polineni, Mandip Dhamoon

doi: 10.1136/svn-2023-003051
Original research
Effectiveness and safety of bridging therapy and endovascular therapy in patients with large cerebral infarctions: from ANGEL-ASPECT

Guangxiong Yuan, Jun Zhang, Zekang Ye, Jingping Sun, Xiaochuan Huo, Yuesong Pan, Mengxing Wang, Xiao Peng, Chanjuan Zheng, Xueyao Lei, Zhongrong Miao, Xueli Cai

doi: 10.1136/svn-2024-003120

May 16, 2024

Original research
Remnant cholesterol is associated with unstable carotid plaque in a neurologically healthy population

Wenbo Li, Yang Liu, Jie Liu, Qirui Guo, Jing Li, Anxin Wang, Huaguang Zheng

doi: 10.1136/svn-2023-002888

May 15, 2024

Original research
Prevalence, genetic and clinical characteristics in first-degree relatives of patients with familial cerebral cavernous malformations in China

Chunwang Li, Lingyun Zhuo, Yaqing Kang, Penghui Liu, Weilin Huang, Qixuan Li, Ke Ma, Shuna Huang, Xinru Lin, Weiheng Zhuang, Haojie Wang, Darong Chen, Huimin Wang, Qiu He, Zhuyu Gao, Xuegang Niu, Yajun Jing, Lingjun Yan, Bin Gao, Dengliang Wang, Shaowei Lin, Siying Wu, Yuanxiang Lin, Dezhi Kang, Fuxin Lin

doi: 10.1136/svn-2023-003004

May 02, 2024

Original research
Delta opioid peptide [D-ala2, D-leu5]-Enkephalin’s ability to enhance mitophagy via TRPV4 to relieve ischemia/reperfusion injury in brain microvascular endothelial cells

Zhongfang Deng, Xiaoyu Chen, Ran Zhang, Lingchao Kong, Yang Fang, Jizheng Guo, Bing Shen, Lesha Zhang

doi: 10.1136/svn-2023-003080

April 22, 2024

Original research
VasCog Screen test: sensitive in detecting cognitive impairment in patients who had a stroke or with heart failure

Nicole Yun Ching Chen, Melissa Yi Ling Tan, Jing Xu, Lijun Zuo, Yanhong Dong

doi: 10.1136/svn-2023-002701

April 03, 2024

Original research
Intelligent cholinergic white matter pathways algorithm based on U-net reflects cognitive impairment in patients with silent cerebrovascular disease

Beini Fei, Yu Cheng, Ying Liu, Guangzheng Zhang, Anyan Ge, Junyi Luo, Shan Wu, He Wang, Jing Ding, Xin Wang

doi: 10.1136/svn-2023-002976
Review
Design of trials in lacunar stroke and cerebral small vessel disease: review and experience with the LACunar Intervention Trial 2 (LACI-2)

Gordon Blair, Jason P Appleton, Iris Mhlanga, Lisa J Woodhouse, Fergus Doubal, Philip M Bath, Joanna M Wardlaw

doi: 10.1136/svn-2023-003022

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