[HTML][HTML] Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

…, R Ono, H Kiyama, AJ Moorhouse, J Nabekura… - Nature …, 2019 - nature.com
Microglia survey brain parenchyma, responding to injury and infections. Microglia also
respond to systemic disease, but the role of blood–brain barrier (BBB) integrity in this process …

Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

…, S Jinno, S Kohsaka, J Nabekura - Journal of …, 2009 - Soc Neuroscience
Recent studies have identified the important contribution of glial cells to the plasticity of
neuronal circuits. Resting microglia, the primary immune effector cells in the brain, dynamically …

[HTML][HTML] Microglia contact induces synapse formation in developing somatosensory cortex

…, AJ Moorhouse, Y Yoshimura, J Nabekura - Nature …, 2016 - nature.com
Microglia are the immune cells of the central nervous system that play important roles in
brain pathologies. Microglia also help shape neuronal circuits during development, via …

[HTML][HTML] Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

…, S Shibata, E Shigetomi, Y Sui, J Nabekura… - Nature …, 2017 - nature.com
Astrocytes become reactive following various brain insults; however, the functions of reactive
astrocytes are poorly understood. Here, we show that reactive astrocytes function as …

Developmental switch from GABA to glycine release in single central synaptic terminals

J Nabekura, S Katsurabayashi, Y Kakazu… - Nature …, 2004 - nature.com
Early in postnatal development, inhibitory inputs to rat lateral superior olive (LSO) neurons
change from releasing predominantly GABA to releasing predominantly glycine into the …

Microglia: actively surveying and shaping neuronal circuit structure and function

…, AJ Moorhouse, A Miyamoto, J Nabekura - Trends in neurosciences, 2013 - cell.com
The traditional role of microglia has been in brain infection and disease, phagocytosing debris
and secreting factors to modify disease progression. Recent evidence extends their role …

Complete Pulp Regeneration After Pulpectomy by Transplantation of CD105+ Stem Cells with Stromal Cell-Derived Factor-1

…, R Ishizaka, A Watanabe, J Nabekura… - … Engineering Part A, 2011 - liebertpub.com
Loss of pulp due to caries and pulpitis leads to loss of teeth and reduced quality of life. Thus,
there is an unmet need for regeneration of pulp. A promising approach is stem cell therapy. …

AMPA–kainate subtypes of glutamate receptor in rat cerebral microglia

M Noda, H Nakanishi, J Nabekura… - Journal of …, 2000 - Soc Neuroscience
Microglial cells were isolated from rat cerebral cortex, and kainate (KA)-induced inward current
was measured at a holding potential of −40 or −60 mV. 6-Cyano-7-nitroquinoxaline-2, 3-…

A novel stem cell source for vasculogenesis in ischemia: subfraction of side population cells from dental pulp

K Iohara, L Zheng, H Wake, M Ito, J Nabekura… - Stem …, 2008 - academic.oup.com
Cell therapy with stem cells and endothelial progenitor cells (EPCs) to stimulate
vasculogenesis as a potential treatment for ischemic disease is an exciting area of research in …

Reduction of kcc2 expression and gabaareceptor-mediated excitation after in vivo axonal injury

J Nabekura, T Ueno, A Okabe, A Furuta… - Journal of …, 2002 - Soc Neuroscience
After axotomy, application of muscimol, a GABA A receptor agonist, induced an increase in
intracellular Ca 2+ ([Ca 2+ ] i ) in dorsal motor neurons of the vagus (DMV neurons). …