User profiles for J.M. Ospel

Johanna Ospel

University of Calgary, University of Basel
Verified email at ucalgary.ca
Cited by 3125

Challenging the ischemic core concept in acute ischemic stroke imaging

M Goyal, JM Ospel, B Menon, M Almekhlafi… - Stroke, 2020 - Am Heart Assoc
… Drs Goyal and Ospel performed in drafting and critical revision of the article. The remaining
… Dr Ospel reports the University of Basel Research Foundation, Julia Bangerter Rhyner …

A review of endovascular treatment for medium vessel occlusion stroke

JM Ospel, M Goyal - Journal of NeuroInterventional Surgery, 2021 - jnis.bmj.com
Medium-vessel occlusions (MeVOs), that is, occlusions of the M2/3 middle cerebral artery,
A2/3 anterior cerebral artery, and P2/3 posterior cerebral artery segments, account for 25%–40…

Management of Acute Ischemic Stroke Due to Large-Vessel Occlusion: JACC Focus Seminar

JM Ospel, JK Holodinsky, M Goyal - Journal of the American College of …, 2020 - jacc.org
Acute ischemic stroke is a severe and life-threatening disease, particularly when caused by
a large-vessel occlusion. The only available 2 treatment options are intravenous alteplase …

Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

…, RA Shah, E Sauvageau, C Zerna, JM Ospel… - The Lancet, 2020 - thelancet.com
Background Nerinetide, an eicosapeptide that interferes with post-synaptic density protein
95, is a neuroprotectant that is effective in preclinical stroke models of ischaemia-reperfusion. …

Machine learning for detecting early infarction in acute stroke with non–contrast-enhanced CT

W Qiu, H Kuang, E Teleg, JM Ospel, SI Sohn… - Radiology, 2020 - pubs.rsna.org
Background Identifying the presence and extent of infarcted brain tissue at baseline plays a
crucial role in the treatment of patients with acute ischemic stroke (AIS). Patients with …

Clinical course of acute ischemic stroke due to medium vessel occlusion with and without intravenous alteplase treatment

JM Ospel, BK Menon, AM Demchuk, MA Almekhlafi… - Stroke, 2020 - Am Heart Assoc
… Dr Ospel performed the drafting and critical revision of the article and figures. Drs Goyal,
Hill, Menon performed conceptualization, drafting, and critical revision of the article. Remaining …

MeVO: the next frontier?

M Goyal, JM Ospel, BK Menon, MD Hill - Journal of neurointerventional …, 2020 - jnis.bmj.com
As several randomized trials have shown the overwhelming benefit of endovascular treatment
(EVT) compared with medical management alone for acute ischemic stroke (AIS) due to …

Prevalence of ipsilateral nonstenotic carotid plaques on computed tomography angiography in embolic stroke of undetermined source

JM Ospel, N Singh, M Marko, M Almekhlafi… - Stroke, 2020 - Am Heart Assoc
… Drs Ospel and Singh contributed to the drafting and critical revision of the manuscript and
figures. Drs Goyal, Hill, and Menon contributed to the conceptualization, drafting, and critical …

Functional outcomes of patients≥ 85 years with acute ischemic stroke following EVT: a HERMES substudy

RV McDonough, JM Ospel, BCV Campbell, MD Hill… - Stroke, 2022 - Am Heart Assoc
Background: Observational studies have shown endovascular treatment (EVT) for acute
ischemic stroke to be effective in the elderly, despite resulting in poorer outcomes and higher …

Optimizing fast first pass complete reperfusion in acute ischemic stroke–the BADDASS approach (BAlloon guiDe with large bore Distal Access catheter with dual …

JM Ospel, O Volny, M Jayaraman… - Expert review of …, 2019 - Taylor & Francis
Introduction: Endovascular therapy is the standard of care for acute ischemic stroke due to
large vessel occlusions. The ultimate goal is to achieve fast first pass complete reperfusion, …