Green tea consumption improves endothelial function but not circulating endothelial progenitor cells in patients with chronic renal failure

CS Park, W Kim, JS Woo, SJ Ha, WY Kang… - International journal of …, 2010 - Elsevier
CS Park, W Kim, JS Woo, SJ Ha, WY Kang, SH Hwang, YW Park, YS Kim, YK Ahn…
International journal of cardiology, 2010Elsevier
This study was designed to determine the effect of green tea consumption in patients with
chronic kidney disease (CKD) on flow-mediated endothelium-dependent vasodilation (FMD)
and the number of circulating endothelial progenitor cells (EPCs). Forty patients with CKD
requiring chronic dialysis were enrolled. The patients were divided into two groups: the
catechin group that consumed green tea (5g/day for 1month) and the control group that
consumed water. The number of EPCs, inflammatory markers, oxidative stress, and FMD …
This study was designed to determine the effect of green tea consumption in patients with chronic kidney disease (CKD) on flow-mediated endothelium-dependent vasodilation (FMD) and the number of circulating endothelial progenitor cells (EPCs). Forty patients with CKD requiring chronic dialysis were enrolled. The patients were divided into two groups: the catechin group that consumed green tea (5g/day for 1month) and the control group that consumed water. The number of EPCs, inflammatory markers, oxidative stress, and FMD were determined at baseline and 4weeks after green tea consumption. Clinical characteristics, oxidative stress, inflammatory markers, and circulating EPCs number were not significantly different. FMD was significantly improved after 4weeks in the catechin group (from 5.68±2.67% to 8.66±3.46%, p=0.002). Short-term green tea consumption induced a rapid improvement in FMD, but did not improve circulating EPC levels in patients with CKD.
Elsevier