Alzheimer disease (AD) is the most common type of dementia, and is currently incurable;
existing treatments for AD produce only a modest amelioration of symptoms. Research into …

China has the largest population of patients with dementia in the world, imposing a heavy
burden on the public and health care systems. More than 100 epidemiological studies on …

Background Evidence on preventing Alzheimer's disease (AD) is challenging to interpret
due to varying study designs with heterogeneous endpoints and credibility. We completed a …

Importance Determining the long-term impact of COVID-19 on cognition is important to
inform immediate steps in COVID-19 research and health policy. Objective To investigate …

Previous studies suggest that gut microbiota is associated with neuropsychiatric disorders,
such as Parkinson's disease, amyotrophic lateral sclerosis, and depression. However …

Background Understanding the long-term effects of coronavirus disease 2019 (COVID-19)
on cognitive function is essential for monitoring the cognitive decline in the elderly …

Objective Inflammation plays a crucial role in the pathogenesis of mild cognitive impairment
(MCI) and Alzheimer's disease (AD). Our study aimed to analyse previous inconsistent …

Polyphenols extracted from grape seeds are able to inhibit amyloid-beta (Aβ) aggregation,
reduce Aβ production and protect against Aβ neurotoxicity in vitro. We aimed to investigate …

Alzheimer's disease (AD) is the most common form of senile dementia and the fourth highest
cause of disability and death in the elderly. Amyloid-β (Aβ) has been widely implicated in the …

Amyloid-beta (Aβ) plays a pivotal role in the pathogenesis of Alzheimer's disease (AD). The
physiological capacity of peripheral tissues and organs in clearing brain-derived Aβ and its …