Stroke in China: advances and challenges in epidemiology, prevention, and management

S Wu, BO Wu, M Liu, Z Chen, W Wang… - The Lancet …, 2019 - thelancet.com
With over 2 million new cases annually, stroke is associated with the highest disability-
adjusted life-years lost of any disease in China. The burden is expected to increase further …

Neuroinflammation: the role and consequences

M Lyman, DG Lloyd, X Ji, MP Vizcaychipi, D Ma - Neuroscience research, 2014 - Elsevier
Neuroinflammation is central to the common pathology of several acute and chronic brain
diseases. This review examines the consequences of excessive and prolonged …

White matter injury in ischemic stroke

Y Wang, G Liu, D Hong, F Chen, X Ji, G Cao - Progress in neurobiology, 2016 - Elsevier
Stroke is one of the major causes of disability and mortality worldwide. It is well known that
ischemic stroke can cause gray matter injury. However, stroke also elicits profound white …

[HTML][HTML] Trial of thrombectomy 6 to 24 hours after stroke due to basilar-artery occlusion

TG Jovin, C Li, L Wu, C Wu, J Chen… - … England Journal of …, 2022 - Mass Medical Soc
Background The effects and risks of endovascular thrombectomy 6 to 24 hours after stroke
onset due to basilar-artery occlusion have not been extensively studied. Methods In a trial …

Transfer of mitochondria from astrocytes to neurons after stroke

K Hayakawa, E Esposito, X Wang, Y Terasaki, Y Liu… - Nature, 2016 - nature.com
Neurons can release damaged mitochondria and transfer them to astrocytes for disposal
and recycling. This ability to exchange mitochondria may represent a potential mode of cell …

Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis

R Meng, K Asmaro, L Meng, Y Liu, C Ma, C Xi, G Li… - Neurology, 2012 - AAN Enterprises
Objective: This study aims to evaluate protective effects of brief repetitive bilateral arm
ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic …

Interleukin-4 is essential for microglia/macrophage M2 polarization and long-term recovery after cerebral ischemia

X Liu, J Liu, S Zhao, H Zhang, W Cai, M Cai, X Ji… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Interleukin-4 (IL-4) is a unique cytokine that may contribute to
brain repair by regulating microglia/macrophage functions. Thus, we examined the effect of …

[HTML][HTML] Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

Y Shi, L Zhang, H Pu, L Mao, X Hu, X Jiang… - Nature …, 2016 - nature.com
The mechanism and long-term consequences of early blood–brain barrier (BBB) disruption
after cerebral ischaemic/reperfusion (I/R) injury are poorly understood. Here we discover …

The China National Stroke Registry for patients with acute cerebrovascular events: design, rationale, and baseline patient characteristics

Y Wang, L Cui, X Ji, Q Dong, J Zeng… - … Journal of Stroke, 2011 - journals.sagepub.com
Background As a leading cause of severe disability and death, stroke places an enormous
burden on the health care system in China. There are limited data on the pattern of current …

[HTML][HTML] The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population

K Jin, JW Simpkins, X Ji, M Leis, I Stambler - Aging and disease, 2015 - ncbi.nlm.nih.gov
Due to the aging of the global population and the derivative increase in aging-related non-
communicable diseases and their economic burden, there is an urgent need to promote …