Autophagy maintains tumour growth through circulating arginine

L Poillet-Perez, X Xie, LE Zhan, Y Yang, DW Sharp… - Nature, 2018 - nature.com
Autophagy captures intracellular components and delivers them to lysosomes, where they
are degraded and recycled to sustain metabolism and to enable survival during starvation …

Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma

X Xie, JY Koh, S Price, E White, JM Mehnert - Cancer discovery, 2015 - AACR
Macroautophagy (autophagy hereafter) may promote survival and growth of spontaneous
tumors, including melanoma. We utilized a genetically engineered mouse model of …

[HTML][HTML] Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma

X Xie, EP White, JM Mehnert - PloS one, 2013 - journals.plos.org
The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR)
pathway promotes melanoma tumor growth and survival while suppressing autophagy, a …

Development of organovermiculite-based adsorbent for removing anionic dye from aqueous solution

X Yu, C Wei, L Ke, Y Hu, X Xie, H Wu - Journal of hazardous materials, 2010 - Elsevier
This paper reports on the development of organovermiculite-based adsorbent for removing
Congo Red (CR), a model anionic dye, from aqueous solution. The organovermiculite was …

An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy

M Michaud, X Xie, JM Bravo-San Pedro… - …, 2014 - Taylor & Francis
There is ample experimental and clinical evidence that chemotherapies are more efficient if
they succeed in (re) activating immune surveillance, hence triggering a long-term immune …

[HTML][HTML] CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma

F Wang, F Zhao, L Zhang, L Xiong, Q Mao, Y Liu… - Molecular Cancer, 2022 - Springer
Background Cell division cycle 6 (CDC6) has been proven to be associated with the
initiation and progression of human multiple tumors. However, it's role in glioma, which is …

Electrospinning polyacrylonitrile (PAN) based nanofiberous membranes synergic with plant antibacterial agent and silver nanoparticles (AgNPs) for potential wound …

P Chen, M Chai, Z Mai, M Liao, X Xie, Z Lu… - Materials Today …, 2022 - Elsevier
Polyacrylonitrile (PAN) nanofiberous membranes incorporated with different content of
Curcumin (Cur), tannic acid and silver nanoparticles (AgNPs) were successfully fabricated …

[HTML][HTML] Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

Y Zhu, C Qu, X Hong, Y Jia, M Lin, Y Luo… - Cell Death & …, 2019 - nature.com
Abstract TRAF-binding domain (Trabid), one of deubiquitination enzymes, was recently
reported to activate Wnt/β-catenin signaling pathway. However, the role of Trabid in tumors …

[HTML][HTML] Single-nucleus transcriptomic mapping of blast-induced traumatic brain injury in mice hippocampus

L Zhang, Q Yang, R Yuan, M Li, M Lv, L Zhang, X Xie… - Scientific Data, 2023 - nature.com
As a significant type of traumatic brain injury (TBI), blast-induced traumatic brain injury (bTBI)
frequently results in severe neurological and psychological impairments. Due to its unique …

Single-nucleus transcriptomic mapping uncovers targets for traumatic brain injury

Q Yang, L Zhang, M Li, Y Xu, X Chen, R Yuan… - Genome …, 2023 - genome.cshlp.org
The subventricular zone (SVZ) is a neurogenic niche that contributes to homeostasis and
repair after brain injury. However, the effects of mild traumatic brain injury (mTBI) on the …