Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data
BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …
Triage, treatment, and transfer: evidence-based clinical practice recommendations and models of nursing care for the first 72 hours of admission to hospital for acute …
S Middleton, R Grimley, AW Alexandrov - Stroke, 2015 - Am Heart Assoc
Organized SU care significantly reduces death and disability3 and improves processes of
care30 as grouping patients together by clinical specialty is associated with improved …
care30 as grouping patients together by clinical specialty is associated with improved …
[HTML][HTML] Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke
H Ma, BCV Campbell, MW Parsons… - … England Journal of …, 2019 - Mass Medical Soc
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …
[HTML][HTML] Identifying the barriers and enablers for a triage, treatment, and transfer clinical intervention to manage acute stroke patients in the emergency department: a …
Background Clinical guidelines recommend that assessment and management of patients
with stroke commences early including in emergency departments (ED). To inform the …
with stroke commences early including in emergency departments (ED). To inform the …
A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits …
H Ma, MW Parsons, S Christensen… - … Journal of Stroke, 2012 - journals.sagepub.com
Background and hypothesis Thrombolytic therapy with tissue plasminogen activator is
effective for acute ischaemic stroke within 4· 5 h of onset. Patients who wake up with stroke …
effective for acute ischaemic stroke within 4· 5 h of onset. Patients who wake up with stroke …
Embedding an enriched environment in an acute stroke unit increases activity in people with stroke: a controlled before–after pilot study
ICM Rosbergen, RS Grimley, KS Hayward… - Clinical …, 2017 - journals.sagepub.com
Objectives: To determine whether an enriched environment embedded in an acute stroke
unit could increase activity levels in acute stroke patients and reduce adverse events …
unit could increase activity levels in acute stroke patients and reduce adverse events …
Quality of acute care and long-term quality of life and survival: the Australian Stroke Clinical Registry
Background and Purpose—Uncertainty exists over whether quality improvement strategies
translate into better health-related quality of life (HRQoL) and survival after acute stroke. We …
translate into better health-related quality of life (HRQoL) and survival after acute stroke. We …
Utility of the hospital frailty risk score derived from administrative data and the association with stroke outcomes
MF Kilkenny, HT Phan, RI Lindley, J Kim, D Lopez… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Conditions associated with frailty are common in people
experiencing stroke and may explain differences in outcomes. We assessed associations …
experiencing stroke and may explain differences in outcomes. We assessed associations …
[HTML][HTML] Development of a theory-informed implementation intervention to improve the triage, treatment and transfer of stroke patients in emergency departments using …
LE Craig, N Taylor, R Grimley, DA Cadilhac… - Implementation …, 2017 - Springer
Background Theoretical frameworks and models based on behaviour change theories are
increasingly used in the development of implementation interventions. Development of an …
increasingly used in the development of implementation interventions. Development of an …
[HTML][HTML] Greater adherence to secondary prevention medications improves survival after stroke or transient ischemic attack: a linked registry study
Background and Purpose: Although a target of 80% medication adherence is commonly
cited, it is unclear whether greater adherence improves survival after stroke or transient …
cited, it is unclear whether greater adherence improves survival after stroke or transient …