Intravenous thrombolysis in unwitnessed stroke onset: MR WITNESS trial results

LH Schwamm, O Wu, SS Song, LL Latour… - Annals of …, 2018 - Wiley Online Library
Objective Most acute ischemic stroke (AIS) patients with unwitnessed symptom onset are
ineligible for intravenous thrombolysis due to timing alone. Lesion evolution on fluid …

Diffuse microvascular dysfunction and loss of white matter integrity predict poor outcomes in patients with acute ischemic stroke

NS Rost, P Cougo, S Lorenzano, H Li… - Journal of Cerebral …, 2018 - journals.sagepub.com
We sought to investigate the relationship between blood–brain barrier (BBB) permeability
and microstructural white matter integrity, and their potential impact on long-term functional …

[HTML][HTML] Association between obesity and COVID-19 mortality and length of stay in intensive care unit patients in Brazil: a retrospective cohort study

VB Paravidino, TH Leite, MFF Mediano, R Sichieri… - Scientific Reports, 2022 - nature.com
The present study aimed to evaluate the association between obesity and COVID-19
mortality and length of stay in ICU patients, and how these associations were modified by …

Integrity of normal-appearing white matter and functional outcomes after acute ischemic stroke

MR Etherton, O Wu, P Cougo, AK Giese, L Cloonan… - Neurology, 2017 - AAN Enterprises
Objective: To characterize the effect of white matter microstructural integrity on cerebral
tissue and long-term functional outcomes after acute ischemic stroke (AIS). Methods …

[HTML][HTML] Brazilian guidelines for endovascular treatment of patients with acute ischemic stroke

OM Pontes-Neto, P Cougo, SCO Martins… - Arquivos de neuro …, 2017 - SciELO Brasil
These guidelines are the result of a joint effort from writing groups of the Brazilian Stroke
Society, the Scientific Department of Cerebrovascular Diseases of the Brazilian Academy of …

Accuracy of the ABC/2 score for intracerebral hemorrhage: systematic review and analysis of MISTIE, CLEAR-IVH, and CLEAR III

AJS Webb, NL Ullman, TC Morgan, J Muschelli… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The ABC/2 score estimates intracerebral hemorrhage (ICH)
volume, yet validations have been limited by small samples and inappropriate outcome …

Clinical outcomes of patients with acute basilar artery occlusion in Brazil: an observational study

FA Dias, FF Alessio-Alves, LH Castro-Afonso… - Journal of Stroke and …, 2017 - Elsevier
Background Intravenous thrombolysis (IVT) and endovascular therapy (EVT) were proven
safe and effective for anterior circulation proximal occlusions. However, the most appropriate …

Role of acute lesion topography in initial ischemic stroke severity and long-term functional outcomes

O Wu, L Cloonan, SJT Mocking, MJRJ Bouts… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Acute infarct volume, often proposed as a biomarker for
evaluating novel interventions for acute ischemic stroke, correlates only moderately with …

Validation of a structured interview for telephone assessment of the modified Rankin Scale in Brazilian stroke patients

JAO Baggio, TEG Santos-Pontelli… - Cerebrovascular …, 2014 - karger.com
Background: The modified Rankin Scale (mRS) is a commonly used scale to assess the
functional outcome after stroke. Several studies on mRS showed good reliability, feasibility …

Subtle white matter intensity changes on fluid-attenuated inversion recovery imaging in patients with ischaemic stroke

P Cougo, H Colares, JG Farinhas… - Brain …, 2024 - academic.oup.com
Leukoaraiosis is a neuroimaging marker of small-vessel disease that is characterized by
high signal intensity on fluid-attenuated inversion recovery MRI. There is increasing …