Sarcopenia, a newly recognized geriatric syndrome, is characterized by age-related decline
of skeletal muscle plus low muscle strength and/or physical performance. Previous studies …

Uncertainty quantification (UQ) methods play a pivotal role in reducing the impact of
uncertainties during both optimization and decision making processes. They have been …

Diarrhoea and pneumonia are the leading infectious causes of childhood morbidity and
mortality. We comprehensively reviewed the epidemiology of childhood diarrhoea and …

Background Information about the distribution of causes of and time trends for child mortality
should be periodically updated. We report the latest estimates of causes of child mortality in …

An approach for genome analysis based on sequencing and assembly of unselected pieces
of DNA from the whole chromosome has been applied to obtain the complete nucleotide …

The genetic architecture of autism spectrum disorder involves the interplay of common and
rare variants and their impact on hundreds of genes. Using exome sequencing, here we …

Platinum-based catalysts have been considered the most effective electrocatalysts for the
hydrogen evolution reaction in water splitting. However, platinum utilization in these …

IDH1 and IDH2 mutations occur frequently in gliomas and acute myeloid leukemia, leading
to simultaneous loss and gain of activities in the production of α-ketoglutarate (α-KG) and 2 …

Autism spectrum disorders (ASD) are believed to have genetic and environmental origins,
yet in only a modest fraction of individuals can specific causes be identified,. To identify …

The RAS/RAF signaling pathway is an important mediator of tumor cell proliferation and
angiogenesis. The novel bi-aryl urea BAY 43-9006 is a potent inhibitor of Raf-1, a member …