During recent decades there have been remarkable advances in biology, in which one of
the most important discoveries is RNA interference (RNAi). RNAi is a specific post …

PURPOSE: To determine the aqueous levels of vascular endothelial growth factor (VEGF)
and pigment epithelium–derived factor (PEDF) in patients with active polypoidal choroidal …

Background Congenital scoliosis is a common type of vertebral malformation. Genetic
susceptibility has been implicated in congenital scoliosis. Methods We evaluated 161 Han …

Objectives The implementation of chromosomal microarray analysis (CMA) in prenatal
testing for all patients has not achieved a consensus. Technical alternatives such as …

Purpose: This study aims to profile the expressions of 156 microRNAs (miRNA) in
hepatocellular carcinoma (HCC) and to characterize the functions of miR-222, the most …

Current non-invasive prenatal screening is targeted toward the detection of chromosomal
abnormalities in the fetus,. However, screening for many dominant monogenic disorders …

As a distinct type of head and neck cancer, non‐keratinizing nasopharyngeal carcinoma
(NPC) is closely associated with EBV infection and massive lymphoid infiltration. The unique …

purpose. To investigate the coding exons in the trabecular meshwork–induced
glucocorticoid response protein (TIGR) gene for mutations in primary open-angle glaucoma …

Purpose: Chromosomal microarray analysis is the gold standard for copy-number variant
(CNV) detection in prenatal and postnatal diagnosis. We aimed to determine whether next …

Objective To report secondary or additional findings arising from introduction of non‐
invasive prenatal testing (NIPT) for aneuploidy by whole genome sequencing as a clinical …