Osteoarthritis (OA) is an age-related chronic degenerative joint disease where the main
characteristics include progressive degeneration of cartilage, varying degrees of synovitis …

Advanced age correlates with higher morbidity and mortality among patients affected with
the novel coronavirus disease 2019 (COVID-19). Because systemic inflammation and …

Brain vascular calcification is a prevalent age-related condition often accompanying
neurodegenerative and neuroinflammatory diseases. The pathogenesis of large-vessel …

Purpose The recommendation strength of the guidelines for mechanical thrombectomy
among patients with large pre-treatment core infarct is weak. We evaluated the safety and …

Ischemic stroke often results in severe injury to white matter structures including the axons,
oligodendroglia, and other glial cells. Immature stages of oligodendroglia, such as …

Hippocampal neuron death is a key factor in vascular dementia (VD) induced by chronic
cerebral hypoperfusion (CCH). Dl-3-n-butylphthalide (NBP) is a multiple-effects drug …

Proprotein convertase subtilisin/kexin 9 (PCSK9) is the ninth member of the proprotein
convertase family. It is an important regulator of cholesterol metabolism. PCSK9 can bind to …

Background and purpose Hematoma expansion (HE) is a critical event following acute
intracerebral hemorrhage (ICH). We aimed to construct a non-contrast computed …

A pulsed electromagnetic field (PEMF) can promote osteogenesis. However, studies have
shown variation in the signal characteristics in terms of waveform type, intensity, frequency …

Background/Aims Chronic cerebral hypoperfusion (CCH) is induced by chronic deficit of
brain perfusion, contributes to a persistent or progressive cognitive dysfunction, which is …