Purpose of the Review To provide an up-to-date review of the incidence of stroke and large
vessel occlusion (LVO) around the globe, as well as the eligibility and access to IV …

Methods A hybrid approach based on established processes described by Glaser15 and by
the National Institutes of Health (http://prevention. nih. gov/cdp/about. aspx) 16 was used to …

Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …

Background Among patients with acute ischemic stroke due to occlusions in the proximal
anterior intracranial circulation, less than 40% regain functional independence when treated …

Background The effect of endovascular thrombectomy that is performed more than 6 hours
after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is …

Background Whether brain imaging can identify patients who are most likely to benefit from
therapies for acute ischemic stroke and whether endovascular thrombectomy improves …

Purpose—The aim of this guideline is to provide a focused update of the current
recommendations for the endovascular treatment of acute ischemic stroke. When there is …

Background: Endovascular treatment with mechanical thrombectomy (MT) is beneficial for
patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is …

Rationale Early reperfusion in patients experiencing acute ischemic stroke is critical,
especially for patients with large vessel occlusion who have poor prognosis without …

Background Multipotent adult progenitor cells are a bone marrow-derived, allogeneic, cell
therapy product that modulates the immune system, and represents a promising therapy for …