User profiles for "author:Chunxiang Zhang"

Chunxiang Zhang/张春祥

Southwest Medical University; Rush University;Sun Yat-sen University;The University of …
Verified email at stu.swmu.edu.cn
Cited by 14613

MicroRNA-21 in cardiovascular disease

Y Cheng, C Zhang - Journal of cardiovascular translational research, 2010 - Springer
Abstract MicroRNA-21 (miR-21) is a highly expressed microRNA (miRNA) in cardiovascular
system. Recent studies have revealed that its expression is deregulated in heart and …

MicroRNomics: a newly emerging approach for disease biology

C Zhang - Physiological genomics, 2008 - journals.physiology.org
Genomic evidence reveals that gene expression in humans is precisely controlled in
cellular, tissue-type, temporal, and condition-specific manners. Completely understanding …

[HTML][HTML] Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment

Y Wu, S Wan, S Yang, H Hu, C Zhang, J Lai… - Journal of …, 2022 - Springer
Synthetic nanoparticles with surface bioconjugation are promising platforms for targeted
therapy, but their simple biological functionalization is still a challenging task against the …

MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation

R Ji, Y Cheng, J Yue, J Yang, X Liu, H Chen… - Circulation …, 2007 - Am Heart Assoc
MicroRNAs (miRNAs) are a recently discovered class of endogenous, small, noncoding
RNAs that regulate about 30% of the encoding genes of the human genome. However, the …

Myeloperoxidase, a leukocyte-derived vascular NO oxidase

JP Eiserich, S Baldus, ML Brennan, W Ma, C Zhang… - Science, 2002 - science.org
Myeloperoxidase (MPO) is an abundant mammalian phagocyte hemoprotein thought to
primarily mediate host defense reactions. Although its microbicidal functions are well …

MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation

Y Cheng, X Liu, J Yang, Y Lin, DZ Xu, Q Lu… - Circulation …, 2009 - Am Heart Assoc
Phenotypic modulation of vascular smooth muscle cells (VSMCs) plays a critical role in the
pathogenesis of a variety of proliferative vascular diseases. Recently, we have found that …

MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy?

Y Cheng, R Ji, J Yue, J Yang, X Liu, H Chen… - The American journal of …, 2007 - Elsevier
MicroRNAs (miRNAs) are a recently discovered class of endogenous, small, noncoding
RNAs that regulate gene expression. Although miRNAs are highly expressed in the heart …

A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia

X Liu, Y Cheng, S Zhang, Y Lin, J Yang… - Circulation …, 2009 - Am Heart Assoc
MicroRNAs (miRNAs) comprise a novel class of endogenous, small, noncoding RNAs that
negatively regulate gene expression. Functionally, an individual miRNA is as important as a …

[HTML][HTML] MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction

S Dong, Y Cheng, J Yang, J Li, X Liu, X Wang… - Journal of Biological …, 2009 - ASBMB
Several recent reports have suggested that microRNAs (miRNAs) might play critical roles in
acute myocardial infarction (AMI). However, the miRNA expression signature in the early …

MicroRNA-21 protects against the H2O2-induced injury on cardiac myocytes via its target gene PDCD4

Y Cheng, X Liu, S Zhang, Y Lin, J Yang… - Journal of molecular and …, 2009 - Elsevier
Reactive oxygen species (ROS)-induced cardiac cell injury via expression changes of
multiple genes plays a critical role in the pathogenesis of numerous heart diseases …