Acute ischaemic stroke interventions: large vessel occlusion and beyond

A Sweid, B Hammoud, S Ramesh, D Wong… - Stroke and vascular …, 2020 - svn.bmj.com
Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust
outcomes achieved by mechanical thrombectomy. Large vessel occlusion (LVO) accounts …

Cerebral ischemic and hemorrhagic complications of coronavirus disease 2019

A Sweid, B Hammoud, K Bekelis… - … Journal of Stroke, 2020 - journals.sagepub.com
Background The coronavirus disease 2019 is associated with neurological manifestations
including stroke. Objectives We present a case series of coronavirus disease 2019 patients …

thrombotic neurovascular disease in COVID-19 patients

A Sweid, B Hammoud, JH Weinberg, M Oneissi… - …, 2020 - journals.lww.com
Study Design Institutional Review Board (IRB) approved the study protocol and waived the
need for informed consent. A retrospective analysis was conducted across 2 institutions …

[PDF][PDF] Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes

EK Sims, A Kulkarni, A Hull, SE Woerner, S Cabrera… - Cell Reports …, 2023 - cell.com
In preclinical models, α-difluoromethylornithine (DFMO), an ornithine decarboxylase (ODC)
inhibitor, delays the onset of type 1 diabetes (T1D) by reducing β cell stress. However, the …

Decreased KATP Channel Activity Contributes to the Low Glucose Threshold for Insulin Secretion of Rat Neonatal Islets

J Yang, B Hammoud, C Li, A Ridler, D Yau, J Kim… - …, 2021 - academic.oup.com
Transitional hypoglycemia in normal newborns occurs in the first 3 days of life and has
clinical features consistent with hyperinsulinism. We found a lower threshold for glucose …

Lessons learned after 760 neurointerventions via the upper extremity vasculature: pearls and pitfalls

A Sweid, JH Weinberg, O Khanna, S Das, J Kim… - …, 2021 - journals.lww.com
BACKGROUND The radial approach has been gaining more widespread use by
neurointerventionalists fueled by data from the cardiology literature showing better safety …

Growth and development in monogenic forms of neonatal diabetes

B Hammoud, SAW Greeley - Current Opinion in Endocrinology …, 2022 - journals.lww.com
Monogenic causes of neonatal diabetes are characterized by variable degree of restriction
of growth in utero because of deficiency of insulin that depends on the specific gene cause …

A comparative study of transradial versus transfemoral approach for flow diversion

JH Weinberg, A Sweid, B Hammoud, A Asada… - Neuroradiology, 2021 - Springer
Purpose Data in neurointerventional literature is extremely limited regarding the safety and
efficacy of flow diversion using transradial access (TRA). We aim to demonstrate the safety …

Incidence and predictors of ophthalmic artery occlusion in intra-arterial chemotherapy for retinoblastoma

A Sweid, K El Naamani, KC Sajja… - Journal of …, 2021 - jnis.bmj.com
Background Retinoblastoma is the most common primary intraocular malignancy in children.
Objective To determine the incidence of ophthalmic artery (OA) occlusion in patients treated …

Discordant Effects of Polyamine Depletion by DENSpm and DFMO on β-cell Cytokine Stress and Diabetes Outcomes in Mice

B Hammoud, JB Nelson, SC May, SA Tersey… - …, 2024 - academic.oup.com
Abstract Type 1 diabetes (T1D) is an autoimmune disease leading to dysfunction and loss of
insulin-secreting β cells. In β cells, polyamines have been implicated in causing cellular …