Genetic determinants of arterial thrombosis

B Voetsch, J Loscalzo - Arteriosclerosis, thrombosis, and vascular …, 2004 - Am Heart Assoc
Arterial thrombosis is a complex disorder that involves multiple genetic and environmental
factors interacting to produce the characteristic phenotype. In the past decades, investigators …

Endogenous mechanisms of inhibition of platelet function

RC Jin, B Voetsch, J Loscalzo - Microcirculation, 2005 - Taylor & Francis
Platelets play an important role in coagulation, in maintenance of hemostasis, and in the
pathophysiology of thrombotic diseases. In response to blood vessel injury, platelets …

Nitric oxide insufficiency and atherothrombosis

B Voetsch, RC Jin, J Loscalzo - Histochemistry and cell biology, 2004 - Springer
Nitric oxide (NO) is a structurally simple compound that participates in a wide range of
biological reactions to maintain normal endothelial function and an antithrombotic …

Ischemic lesion volumes in acute stroke by diffusion‐weighted magnetic resonance imaging correlate with clinical outcome

KO Löuvbld, AE Baird, G Schlaug… - Annals of Neurology …, 1997 - Wiley Online Library
Diffusion‐weighted magnetic resonance imaging detects ischemic injury within minutes after
onset, and has been used to demonstrate drug efficacy in animal models of stroke. In 50 …

Basilar artery occlusive disease in the New England Medical Center posterior circulation registry

B Voetsch, LD DeWitt, MS Pessin… - Archives of …, 2004 - jamanetwork.com
Background Most reports on basilar artery (BA) occlusive disease have retrospectively
described single cases or small patient series. Objective To assess clinical and vascular …

[HTML][HTML] Determinants of human plasma glutathione peroxidase (GPx-3) expression

C Bierl, B Voetsch, RC Jin, DE Handy… - Journal of Biological …, 2004 - ASBMB
Plasma glutathione peroxidase (GPx-3) is a selenocysteine-containing protein with
antioxidant properties. GPx-3 deficiency has been associated with cardiovascular disease …

Promoter Polymorphisms in the Plasma Glutathione Peroxidase (GPx-3) Gene: A Novel Risk Factor for Arterial Ischemic Stroke Among Young Adults and Children

B Voetsch, RC Jin, C Bierl, KS Benke, G Kenet… - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Plasma glutathione peroxidase (GPx-3)–deficiency increases
extracellular oxidant stress, decreases bioavailable nitric oxide, and promotes platelet …

[HTML][HTML] Glucose-6-phosphate dehydrogenase modulates vascular endothelial growth factor-mediated angiogenesis

JA Leopold, J Walker, AW Scribner, B Voetsch… - Journal of Biological …, 2003 - ASBMB
Glucose-6-phosphate dehydrogenase (G6PD), the first enzyme of the pentose phosphate
pathway, is the principal intracellular source of NADPH. NADPH is utilized as a cofactor by …

Paraoxonase 192 Gln→ Arg polymorphism: an independent risk factor for nonfatal arterial ischemic stroke among young adults

B Voetsch, KS Benke, BP Damasceno, LH Siqueira… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—The etiology of arterial ischemic stroke (AIS) in the young
remains unknown in one third of patients. Serum paraoxonase (PON1) is an HDL …

Insular cortex infarction in acute middle cerebral artery territory stroke: predictor of stroke severity and vascular lesion

JN Fink, MH Selim, S Kumar, B Voetsch… - Archives of …, 2005 - jamanetwork.com
Background Insula infarction is an early computed tomographic sign of middle cerebral
artery (MCA) territory stroke and may affect cardiovascular autonomic function. Objective To …