Intracerebral haemorrhage associated with antithrombotic treatment: translational insights from experimental studies
A Lauer, W Pfeilschifter, CB Schaffer, EH Lo… - The Lancet …, 2013 - thelancet.com
Little is known about the pathophysiology of intracerebral haemorrhage that occurs during
anticoagulant treatment. In observational studies, investigators have reported larger …
anticoagulant treatment. In observational studies, investigators have reported larger …
Statins in intracerebral hemorrhage
A Lauer, SM Greenberg, ME Gurol - Current atherosclerosis reports, 2015 - Springer
While statins play an indisputable role in primary and secondary prevention of ischemic
cardiovascular and cerebrovascular disease, a concern exists regarding a possible …
cardiovascular and cerebrovascular disease, a concern exists regarding a possible …
Total magnetic resonance imaging burden of small vessel disease in cerebral amyloid angiopathy: an imaging-pathologic study of concept validation
A Charidimou, S Martinez-Ramirez, YD Reijmer… - JAMA …, 2016 - jamanetwork.com
Importance Cerebral amyloid angiopathy (CAA) is characteristically associated with
magnetic resonance imaging (MRI) biomarkers of small vessel brain injury, including strictly …
magnetic resonance imaging (MRI) biomarkers of small vessel brain injury, including strictly …
Intravenous thrombolysis in unwitnessed stroke onset: MR WITNESS trial results
Objective Most acute ischemic stroke (AIS) patients with unwitnessed symptom onset are
ineligible for intravenous thrombolysis due to timing alone. Lesion evolution on fluid …
ineligible for intravenous thrombolysis due to timing alone. Lesion evolution on fluid …
Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study
Cerebral amyloid angiopathy is a common neuropathological finding in the ageing human
brain, associated with cognitive impairment. Neuroimaging markers of severe cerebral …
brain, associated with cognitive impairment. Neuroimaging markers of severe cerebral …
Clinical imaging factors associated with infarct progression in patients with ischemic stroke during transfer for mechanical thrombectomy
G Boulouis, A Lauer, AK Siddiqui, A Charidimou… - JAMA …, 2017 - jamanetwork.com
Importance When transferred from a referring hospital (RH) to a thrombectomy-capable
stroke center (TCSC), patients with initially favorable imaging profiles (Alberta Stroke …
stroke center (TCSC), patients with initially favorable imaging profiles (Alberta Stroke …
Delays in the air or ground transfer of patients for endovascular thrombectomy
Background and Purpose—For suspected large vessel occlusion patients efficient transfer to
centers that provide endovascular therapy (ET) is critical to maximizing treatment …
centers that provide endovascular therapy (ET) is critical to maximizing treatment …
[HTML][HTML] Hematopoietic stem-cell gene therapy is associated with restored white matter microvascular function in cerebral adrenoleukodystrophy
A Lauer, SL Speroni, M Choi, X Da, C Duncan… - Nature …, 2023 - nature.com
Blood-brain barrier disruption marks the onset of cerebral adrenoleukodystrophy (CALD), a
devastating cerebral demyelinating disease caused by loss of ABCD1 gene function. The …
devastating cerebral demyelinating disease caused by loss of ABCD1 gene function. The …
Anticoagulation with the oral direct thrombin inhibitor dabigatran does not enlarge hematoma volume in experimental intracerebral hemorrhage
A Lauer, FA Cianchetti, EM Van Cott, F Schlunk… - Circulation, 2011 - Am Heart Assoc
Background—The direct thrombin inhibitor dabigatran etexilate (DE) may constitute a future
replacement of vitamin K antagonists for long-term anticoagulation. Whereas warfarin …
replacement of vitamin K antagonists for long-term anticoagulation. Whereas warfarin …
Intracerebral Hemorrhage Formation Under Direct Oral Anticoagulants: Clinical and Translational Evidence
C Foerch, EH Lo, K van Leyen, A Lauer, JH Schaefer - Stroke, 2019 - Am Heart Assoc
Methods Clinical and experimental studies were identified by performing a PubMed and
EMBASE database search using the following term:(anticoagulation OR noac OR vka OR …
EMBASE database search using the following term:(anticoagulation OR noac OR vka OR …