Gut microbiota impact on stroke outcome: Fad or fact?

J Cereb Blood Flow Metab. 2016 May;36(5):891-8. doi: 10.1177/0271678X16636890. Epub 2016 Mar 4.

Abstract

Microbiota and its contribution to brain function and diseases has become a hot topic in neuroscience. We discuss the emerging role of commensal bacteria in the course of stroke. Further, we review potential pitfalls in microbiota research and their impact on how we interpret the available evidence, emerging results, and on how we design future studies.

Keywords: Brain ischemia; brain trauma; immunology; physiology; regeneration and recovery.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood-Brain Barrier / metabolism
  • Gastrointestinal Microbiome / immunology*
  • Gastrointestinal Tract / immunology
  • Gastrointestinal Tract / microbiology
  • Humans
  • Stroke / immunology*