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Wall Enhancement of the Intracranial Aneurysms Revealed by Magnetic Resonance Vessel Wall Imaging Using Three-Dimensional Turbo Spin-Echo Sequence with Motion-Sensitized Driven-Equilibrium: A Sign of Ruptured Aneurysm?

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Abstract

Purpose

Wall enhancement of saccular cerebral aneurysms has not been researched sufficiently. Our purpose of this study was to investigate the incidence of aneurysmal wall enhancement by the three-dimensional turbo spin-echo sequence with motion-sensitized driven equilibrium (MSDE-3D-TSE) imaging after gadolinium injection.

Methods

We retrospectively reviewed the pre- and postcontrast MSDE-3D-TSE images of 117 consecutive patients with intracranial aneurysms from September 2011 to July 2013. A total of 61 ruptured and 83 unruptured aneurysms of 61 patients with subarachnoid hemorrhage (SAH) and 56 non-SAH patients were enrolled in this study. We evaluated the wall enhancement of each aneurysm on postcontrast MSDE-3D-TSE images compared with precontrast images. We classified the aneurysmal wall enhancement into three groups as “Strong enhancement,” “Faint enhancement,” and “No enhancement.”

Results

“Strong/Faint enhancement” of the aneurysm was detected in 73.8/24.6 % of the ruptured aneurysms and 4.8/13.3 % of the unruptured aneurysms. “No enhancement” was found in 1.6 % of the ruptured aneurysms and 81.9 % of the unruptured aneurysms.

Conclusions

By magnetic resonance vessel wall imaging using the MSDE-3D-TSE sequence, wall enhancement was frequently observed on ruptured aneurysms. Therefore, aneurysmal wall enhancement may be an indicator of the ruptured condition, which is useful information for managing patients with SAH.

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Acknowledgments

The authors would like to thank Dr. Paul Hollister for the English editing of the manuscript.

Ethical Standards and Patient Consent

The authors declare that all human and animal studies have been approved by the ethical committee of their hospital and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The authors also declare that all patients gave informed consent prior to inclusion in this study.

Conflict of interest

M. Obara is an employee of Philips Electronics Japan, Ltd.

Author information

Authors and Affiliations

  1. Department of Interventional and Diagnostic Neuroradiology, Yamagata City Hospital Saiseikan, 1-3-26 Nanukamachi, 990-8533, Yamagata city, Yamagata, Japan

    S. Nagahata & M. Nagahata MD, PhD

  2. Philips Electronics Japan Ltd., Tokyo, Japan

    M. Obara

  3. Department of Neurosurgery, Yamagata City Hospital Saiseikan, Yamagata, Japan

    R. Kondo, S. Sato, W. Mouri & S. Saito

  4. Department of Radiology, Yamagata City Hospital Saiseikan, Yamagata, Japan

    N. Minagawa & S. Sato

  5. Department of Neurosurgery, Yamagata University Faculty of Medicine, Yamagata, Japan

    T. Kayama

Authors
  1. S. Nagahata
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  2. M. Nagahata MD, PhD
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  3. M. Obara
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  4. R. Kondo
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  5. N. Minagawa
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  6. S. Sato
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  7. S. Sato
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  8. W. Mouri
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  9. S. Saito
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  10. T. Kayama
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Corresponding author

Correspondence to M. Nagahata MD, PhD.

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Nagahata, S., Nagahata, M., Obara, M. et al. Wall Enhancement of the Intracranial Aneurysms Revealed by Magnetic Resonance Vessel Wall Imaging Using Three-Dimensional Turbo Spin-Echo Sequence with Motion-Sensitized Driven-Equilibrium: A Sign of Ruptured Aneurysm?. Clin Neuroradiol 26, 277–283 (2016). https://doi.org/10.1007/s00062-014-0353-z

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  • DOI: https://doi.org/10.1007/s00062-014-0353-z

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