Association between haematocrit and mortality
| In-hospital mortality | 30-day mortality | 6-month mortality | 1-year mortality* | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Age† | 1.63 (1.26 to 2.11) | 1.870 (1.56 to 2.25) | 1.56 (1.36 to 1.78) | 1.47 (1.305 to 1.65) |
| Haematocrit (%) | ||||
| ≤27 | 3.46 (1.30 to 9.22) | 2.47 (1.20 to 5.05) | 2.54 (1.39 to 4.63) | 2.58 (1.46 to 4.55) |
| 28–32 | 1.66 (0.75 to 3.67) | 1.37 (0.82 to 2.30) | 2.19 (1.49 to 3.23) | 2.05 (1.43 to 2.95) |
| 33–37 | 1.67 (0.94 to 3.00) | 0.97 (0.65 to 1.45) | 1.42 (1.06 to 1.91) | 1.30 (1.00 to 1.70) |
| 38–42 | 1.00 | 1.00 | 1.00 | 1.00 |
| 43–47 | 1.17 (0.63 to 2.16) | 0.83 (0.55 to 1.27) | 0.84 (0.61 to 1.15) | 0.94 (0.72 to 1.23) |
| ≥48 | 2.89 (1.39 to 6.00) | 1.17 (0.64 to 2.14) | 0.84 (0.51 to 1.39) | 0.68 (0.43 to 1.07) |
| Platelet count 10 9 per liter | 2.92 (1.00 to 8.50) | 3.75 (1.69 to 8.31) | 2.63 (1.33 to 5.19) | 2.40 (1.26 to 4.56) |
| Charlson Index | 0.97 (0.82 to 1.14) | 1.019 (0.91 to 1.14) | 1.17 (1.08 to 1.28) | 1.21 (1.12 to 1.31) |
| Modified APACHE-III‡ | 1.04 (1.02 to 1.07) | 1.04 (1.02 to 1.06) | 1.02 (1.01 to 1.04) | 1.03 (1.01 to 1.04) |
| NIHSS | 1.13 (1.11 to 1.15) | 1.145 (1.12 to 1.16) | 1.12 (1.11 to 1.14) | 1.11 (1.09 to 1.13) |
| Atrial fibrillation | 1.03 (0.57 to 1.86) | 1.13 (0.75 to 1.69) | 1.41 (1.04 to 1.92) | 1.44 (1.08 to 1.91) |
| Cancer | 2.28 (1.16 to 4.50) | 2.06 (1.27 to 3.33) | 1.84 (1.27 to 2.67) | 1.91 (1.36 to 2.69) |
| Heart disease§ | 1.38 (0.87 to 2.18) | 1.43 (1.03 to 1.97) | 1.07 (0.84 to 1.37) | 1.11 (0.89 to 1.38) |
| COPD/asthma/bronchitis | 0.93 (0.52 to 1.66) | 1.23 (0.84 to 1.80) | 0.95 (0.71 to 1.28) | 0.96 (0.74 to 1.26) |
| Kidney disease requiring dialysis¶ | NA | 0.80 (0.23 to 2.77) | 0.81 (0.33 to 1.99) | 0.80 (0.35 to 1.83) |
| Oxygen saturation <90% | 1.30 (0.44 to 3.83) | 1.65 (0.72 to 3.82) | 1.66 (0.80 to 3.44) | 1.25 (0.61 to 2.54) |
| Pneumonia | 1.54 (0.56 to 4.25) | 3.12 (1.49 to 6.55) | 4.45 (2.27 to 8.90) | 4.27 (2.16 to 8.45) |
*Mortality model discrimination and calibration: in-hospital (C=0.91; HLGOF=0.97); 30-day (C=0.83; HLGOF=0.82); 6-month (C=0.86; HLGOF=0.73); 1-year (C=0.88; HLGOF=0.43).
†Age, in 10-year increments.
‡Modified APACHE-III calculated without haematocrit values.
§Heart disease is a composite of history of coronary heart disease, myocardial infarction, coronary artery bypass graft surgery, percutaneous transluminal coronary angioplasty/coronary artery stenting, congestive heart failure, carotid artery stenosis and peripheral artery disease.
¶ORs for kidney disease requiring dialysis could not be generated due to the absence of in-hospital mortality events among patients with this comorbidity.
APACHE-III, Acute Physiology and Chronic Health Evaluation-III; C, C-statistic; COPD, chronic obstructive pulmonary disease; HLGOF, Hosmer-Lemeshow goodness of fit; NIHSS, National Institutes of Health Stroke Scale; NA, not available.