Baseline parameter | LAO (n=2042) | Non-LAO (n=2881) | P values | ||
No/Total | Median or proportion (%) | No./Total | Median or proportion (%) | ||
Age | 2035 | 72 | 2881 | 71 | 0.189 |
Gender, female | 965/2042 | 47.3% | 1261/2881 | 43.8% | 0.015 |
NIHSS at baseline | 2042 | 16 | 2881 | 8 | <0.01 |
Weight, kg | 2042 | 75 | 2881 | 78 | <0.01 |
Glucose, mmol/L | 1892 | 6.7 | 2800 | 6.6 | 0.824 |
Total cholesterol | 1259 | 4.6 | 2119 | 4.7 | 0.165 |
Systolic BP | 1963 | 150 | 2848 | 156 | <0.01 |
Diastolic BP | 1963 | 80 | 2848 | 84 | <0.01 |
Prestroke mRS score>2 | 81/1978 | 4.1% | 135/2800 | 4.8% | 0.234 |
Hypertension | 1345/2033 | 66.2% | 1958/2876 | 68.1% | 0.157 |
Diabetes | 383/2033 | 18.8% | 648/2876 | 22.5% | <0.01 |
Hyperlipidaemia | 635/2008 | 31.6% | 912/2857 | 31.9% | 0.826 |
Current smoker | 319/1948 | 16.4% | 458/2789 | 16.4% | 0.967 |
Previous stroke | 204/2032 | 10.0% | 396/2870 | 13.8% | <0.01 |
Previous TIA | 106/2032 | 5.2% | 177/2870 | 6.2% | 0.160 |
Atrial fibrillation | 495/2026 | 24.4% | 486/2867 | 17.0% | <0.01 |
Heart failure | 176/2021 | 8.7% | 201/2864 | 7.0% | 0.029 |
Aspirin | 566/2026 | 27.9% | 931/2868 | 32.5% | <0.01 |
Oral anticoagulants | 158/2031 | 7.8% | 105/2871 | 3.7% | <0.01 |
Clopidogrel | 119/2029 | 5.9% | 165/2870 | 5.7% | 0.864 |
Oral antidiabetics | 218/1999 | 10.9% | 404/2852 | 14.2% | <0.01 |
Statins | 551/2026 | 27.2% | 803/2871 | 28.0% | 0.551 |
LAO, any internal carotid artery occlusion and/or M1 occlusion and/or basilar occlusion; non-LAO, M2 M3, ACA, PCA or none.
BP, blood pressure; LAO, large artery occlusion; mRS, modified Rankin Score; NIHSS, National Institutes of Health Stroke Scale.