Table 3

Studies evaluating the risk of stroke in patients with ACS using carotid plaque MRI

Study (year)Number of patientsMean follow-up (months)HR (95% CI) for stroke
Takaya et al 56 (2006)15438.2IPH: 5.2 (1.6 to 7.3)
TRFC: 2.2 to 132.0
LRNC: 0.6 to 33.7
Singh et al 53 (2009)9824.9IPH: 2.48 to 4.71
Sadat et al 57 (2010)6116.9IPH: 1.27 to 26.77
TRFC: 7.39 (1.61 to 33.82)
LRNC: 1.75 (0.55 to 5.54)
Mono et al 54 (2012)6518.9IPH: 0.03 (0.00 to 86.62)
TRFC: 1.103 (0.11 to 10.70)
LRNC: 7.2 (1.12 to 46.28)
Kwee et al 55 (2013)12612.0IPH: 3.5 (1.06 to 11.96)
TRFC: 5.8 (1.91 to 17.32)
LRNC: 3.2 (1.08 to 9.50)
Hosseini et al 58 (2013)17917.5IPH: 12 (4.8 to 30.1)
  • ACS, asymptomatic carotid stenosis; IPH, intraplaque haemorrhage; LRNC, lipid-rich necrotic core; TRFC, thinning/rupture of the fibrous cap.