Table 2

ORs (95% CIs) for 30-day death/stroke for CEA versus CAS in EVA-3S, SPACE, ICSS and CREST*

TrialOR (95% CI)
EVA-3S8 0.38 (0.16 to 0.84)
SPACE9 0.89 (0.55 to 1.42)
ICSS11 0.53 (0.35 to 0.80)
CREST*18 0.52 (0.29 to 0.92)
Meta-analysis0.59 (0.42 to 0.81)
  • *Only symptomatic patients from CREST were included. 

  • CAS, carotid artery stenting; CEA, carotid endarterectomy; CREST, Carotid Revascularisation versus Stenting Trial; EVA-3S,  Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis; SPACE, Stent-Protected Angioplasty versus Carotid Endarterectomy.