Table 3

Average hospital costs ($2013) for patients aged 18–64 years with a primary diagnosis of acute ischaemic stroke by intravenous tissue plasminogen activator (IV tPA) status, 2010–2013 MarketScan Commercial Claim Inpatient Database

		IV tPA status
	Total (N=39 149)	Non-tPA group (A) (N=36 603)	IV tPA group (B) (N=2546)	Differences (B–A) (p Value)
Total	20 331	19 563	31 369	11 806 (<0.01)
Age, years
18–44	22 316	21 581	31 347	9767 (<0.01)
45–54	20 165	19 456	30 428	10 972 (<0.01)
55–64	19 981	19 182	31 845	12 663 (<0.01)
Gender
Female	20 210	19 450	31 137	11 687 (<0.01)
Male	20 417	19 644	31 534	11 891 (<0.01)
Metropolitan statistical area
No	18 683	18 091	31 220	13 129 (<0.01)
Yes	20 693	19 895	31 390	11 495 (<0.01)
Region
West	24 419	23 572	34 735	11 164 (<0.01)
Northeast	21 456	20 753	32 005	11 252 (<0.01)
North central	19 770	19 048	29 949	10 901 (<0.01)
South	19 056	18 270	30 895	12 625 (<0.01)
Charlson comorbidity index
0–2	17 833	17 119	27 842	10 723 (<0.01)
3–4	21 293	20 384	33 063	12 679 (<0.01)
5 or higher	22 253	21 661	33 745	12 084 (<0.01)
Length of stay, days
<2	11 882	11 638	19 934	8296 (<0.01)
2–4	16 218	15 560	25 525	9965 (<0.01)
≥5	33 469	32 611	42 822	10 211 (<0.01)
Discharge destination
Home	17 065	16 440	27 164	10 724 (<0.01)
Rehabilitation facility	28 766	27 618	39 330	11 711 (<0.01)
Short-term hospital/SNF/other*	29 710	28 939	41 613	12 674 (<0.01)
Expired	40 574	40 633	40 055	−578 (0.87)

All numbers except p values are 2012 US dollar.
*SNF stands for skilled-nursing facility. Other discharge status includes transferring to federal hospital, critical access hospital, hospice, long-term care facility and all other discharge status.