Categories | PTAS group (n=400) | Medical group (n=409) | P value |
Age | 59.31 (10.35) | 58.09 (11.09) | 0.11 |
Sex | |||
Male | 255 (63.75%) | 280 (68.46%) | 0.16 |
Female | 145 (36.25%) | 129 (31.54%) | |
Ethnicity origin | |||
Black | 55 (13.75%) | 49 (11.98%) | 0.55 |
White | 160 (40.00%) | 162 (39.61%) | |
Yellow | 180 (45.00%) | 188 (45.97%) | |
Other | 5 (1.25%) | 10 (2.44%) | |
Medical history | |||
Body mass index | 28.72 (5.73 | 28.30 (5.60 | 0.31 |
Hypertension | 317 (79.25%) | 328 (80.20%) | 0.79 |
Diabetes | 162 (52.43%) | 147 (47.57%) | 0.19 |
Coronary artery disease | 66 (16.50%) | 78 (19.07%) | 0.36 |
Lipid disorder | 213 (53.25%) | 223 (54.52%) | 0.72 |
Peripheral artery disease | 9 (2.25%) | 15 (3.67%) | 0.30 |
Received antiplatelet therapy prior to latest qualifying event | 193 (48.25%) | 188 (45.97%) | 0.53 |
Smoking history | |||
Former | 118 (29.50%) | 118 (28.85%) | 0.21 |
Current | 95 (23.75%) | 119 (29.10%) | |
never | 186 (46.50%) | 172 (42.05%) | |
Time from latest ischaemic event to randomisation, day | 30.81 (41.58 | 33.71 (46.23 | 0.35 |
Qualifying event | |||
TIA | 169 (42.25%) | 152 (37.16%) | 0.15 |
Stroke | 231 (57.75%) | 257 (62.84%) | |
Stenosis rate of symptomatic qualifying artery % stenosis | 79.74 (6.25) | 79.23 (6.39) | 0.25 |
Symptomatic qualifying artery | |||
ICA | 60 (15.00%) | 66 (16.14%) | 0.05 |
MCA | 157 (39.25%) | 184 (44.99%) | |
VA | 84 (21.00%) | 56 (13.69%) | |
BA | 99 (24.75%) | 103 (25.18%) | |
Distribution, % stenosis | |||
70–79 | 213 (53.25%) | 232 (56.72%) | 0.45 |
80–89 | 157 (39.25%) | 143 (34.96%) | |
90–99 | 30 (7.50%) | 34 (8.31%) | |
mRS score | 0.88 (0.95) | 0.90 (0.96 | 0.74 |
NIHSS score | 1.15 (1.86) | 1.08 (1.75) | 0.58 |
LDL-C (mmol/L%) | 2.34 (1.08) | 2.35 (2.44) | |
HDL-C (mmol/L%) | 1.67 (0.69) | 1.69 (0.69) | 0.56 |
Data are mean±SD, n (%)
BA, basilar artery; HDL-C, high-density lipoprotein cholesterol; ICA, internal carotid artery; LDL-C, low-density lipoprotein cholesterol; MCA, middle cerebral artery; mRS, modified Rankin scale; NIHSS, National Institutes of Health Stroke Scale; PTAS, percutaneous transluminal angioplasty and stenting; TIA, transient ischaemic attack; VA, vertebral artery.