Table 2

Advantages and disadvantages of large animal and rodent models for poststroke rehabilitation

AnimalsAdvantagesDisadvantagesRefs
Large animalsCloser to human ischaemic stroke, easier to perform rehabilitation training and evaluating, suitable to test different rehabilitation methodsLarge individual differences and model variability, high requirements in rehabilitation equipment and researchers 25–28
RodentsAbundant animal sources, stable postoperative detection methodsResults are difficult to translate into clinics due to species limitations