Table 3

Advantages and disadvantages of in vitro ischaemic stroke models

Stroke modelsAdvantagesDisadvantagesRefs
Oxygen glucose deprivationDirectly study cells and intracellular interactions via cocultureOnly mimic a part of ischaemic pathophysiology and injury 53 54
Excitotoxicity model
Oxidative phosphorylation blocking model
Directly study cells and intracellular interactions via cocultureOnly mimic a part of ischaemic pathophysiology and injury 55 56