Studies evaluating the association between carotid plaque echolucency and risk of ipsilateral stroke
| Study (year) | Number of patients | Mean follow-up (months) | Ipsilateral stroke RR (95% CI) |
| O’Holleran et al19 (1987) | 293 | 46 | 5.12 (2.01 to 13.04) |
| Polak et al20 (1998) | 4886 | 39.6 | 1.96 (1.25 to 2.90) |
| Mathiesen et al21 (2001) | 177 | 36 | 3.85 (0.46 to 32.28) |
| Grønholdt et al22 (2001) | 111 | 52.8 | 0.87 (0.34 to 2.23) |
| Nicolaides et al23 (2005) | 1092 | 37.1 | 2.23 (1.28 to 3.87) |
| Topakian et al24 (2011) | 435 | 21.8 | 6.61 (1.42 to 30.75) |
| Silvestrini et al25 (2013) | 621 | 27* | 2.37 (1.14 to 4.92) |
| Huibers et al26 (2016) | 814 | 60 | 2.52 (1.20 to 5.25) |
*Median follow-up.
RR, relative risk.