Clinical characteristics of included patients across different subgroups
| Variables | All patients (N=326) | Patients with DWI (N=228) | DWI infarct volume >70 mL (N=40) |
| Age, years | 66.0 (56.8–74.0) | 67.5 (57.3–75.0) | 66.0 (57.5–76.5) |
| Men | 205 (62.9%) | 144 (63.2%) | 30 (75.0%) |
| Hypertension | 196 (60.1%) | 132 (57.9%) | 17 (42.5%) |
| Diabetes mellitus | 72 (22.1%) | 43 (18.9%) | 6 (15.0%) |
| Hyperlipidaemia | 25 (7.7%) | 16 (7.0%) | 3 (7.5%) |
| Atrial fibrillation | 74 (22.7%) | 51 (22.4%) | 7 (17.5%) |
| NIHSS at admission | 15.0 (9.5–20.0) | 9.0 (15.0–19.0) | 14.0 (17.0–21.0) |
| Intravenous thrombolysis | 95 (29.1%) | 75 (32.9%) | 19 (47.5%) |
| Anterior circulation large vessel occlusion | 297 (91.1%) | 202 (88.6%) | 39 (97.5%) |
| RAPID CBF <30 mL | 6.0 (0.0–23.0) | 5.0 (0.0–18.0) | 40.5 (10.3–71.5) |
| iStroke CBF <30 mL | 22.3 (7.2–37.6) | 18.8 (3.9–32.1) | 46.7 (20.4–70.1) |
| RAPID Tmax >6 s | 135.5 (83.8–187.5) | 121.0 (66.3–177.0) | 169.0 (103.7–215.8) |
| iStroke Tmax >6 s | 131.2 (67.9–183.5) | 123.9 (57.4–173.6) | 165.7 (125.4–219.1) |
| Onset to first CTP time | 231.0 (142.3–408.5) | 228.0 (141.8–390.3) | 219.0 (105.0–369.0) |
| CT to first recanalisation time | 118.0 (85.0–152.0) | 118.0 (85.0–152.0) | 125.0 (71.0–153.0) |
| CT to MRI time | 3506.0 (2540.0–5075.0) | 3509.0 (2540.0–5079.0) | 3639.5 (2583.5–5066.5) |
| Infarct volume on DWI | 23.9 (10.8–52.1) | 23.9 (10.8–52.1) | 91.6 (77.9–113.9) |
Data are described as n (%) or median (IQR) as appropriate.
CBF, cerebral blood flow; CTP, CT perfusion; DWI, diffusion-weighted imaging; NIHSS, National Institutes of Health Stroke Scale; Tmax, time-to-maximum.