Table 2

Generalised linear mixed analysis of independent variables associated with the number of microembolic signals in patients with mechanical heart valves

Multivariable analysis
Characteristics	Preoxygenation phase		Postoxygenation phase
Characteristics	OR (95% CI)	P value	OR (95% CI)	P value
Age	0.88 (0.82 to 0.93)	0.000	0.92 (0.87 to 0.98)	0.008
Female	0.37 (0.10 to 1.38)	0.14	1.19 (0.29 to 4.88)	0.80
Currently smoking	4.62 (1.79 to 11.93)	0.002	8.53 (1.03 to 70.55)	0.04
Atrial fibrillation	0.54 (0.25 to 1.16)	0.11	0.69 (0.30 to 1.60)	0.37
Warfarin and aspirin	2.57 (0.75 to 8.88)	0.13	3.80 (1.50 to 9.66)	0.007
Operation to monitoring period	1.01 (1.00 to 1.01)	0.01	1.01 (1.007 to 1.015)	0.00
Location of valve replacement
Mitral location*	0.06 (0.01 to 0.33)	0.002	0.11 (0.005 to 2.30)	0.14
>1 Mechanical valve*	3.63 (1.27 to 10.41)	0.017	2.72 (0.51 to 13.90)	0.22
INR	1.07 (0.76 to 1.50)	0.70	0.75 (0.57 to 1.00)	0.05
tHcy	1.34 (1.07 to 1.68)	0.009	1.40 (1.07 to 1.83)	0.01

Reference group: *aorta.
INR, international normalised ratio; tHcy, total homocysteine.