Table 1

Baseline characteristics of the enrolled patients in the Ginkgo biloba extract and control groups

GBE group (n=177)Control group (n=165)Difference (P value)
Age (years) (mean±SEM)64.53±0.7663.27±0.830.265
Women (n (%))120 (67.80)96 (58.18)0.066
SBP (mm Hg) (mean±SEM)143.09±1.54145.89±1.510.196
DBP (mm Hg) (mean±SEM)82.34±0.8684.30±1.010.141
Stroke history (n (%))143 (80.79)134 (81.21)0.921
Hypertension history
(n (%))
108 (61)107 (64.8)0.537
Diabetes mellitus history (n (%))42 (23.7)46 (27.9)0.770
CHD history (n (%))8 (4.5)5 (3)0.518
Hyperlipidaemia history (n (%))7 (3.5)5 (3)0.216
FBS (mmol/L) (mean±SEM)6.65±0.226.71±0.220.853
BUN (µmol/L) (mean±SEM)5.23±0.137.39±1.780.224
Creatinine (µmol/L)(mean±SEM)73.45±1.7271.24±2.310.451
ALT (U/L) (mean±SEM)18.80±0.8320.90±1.090.129
AST (U/L) (mean±SEM)19.58±0.6220.43±0.810.402
Triglycerides* (n (%))16 (9.04)20 (12.12)0.419
Thrombin time*(s) (n (%))1 (0.56)1 (0.61)0.493
APTT (s) (mean±SEM)26.60±0.5125.61±0.450.162
Fibrinogen (g/L) (mean±SEM)4.56±1.383.76±0.820.635
NIHSS median (P25, P75)5 (4, 7)5 (4, 7)0.625
BI (mean±SEM)60.56±1.8057.79±1.850.284
Independent mRS (n (%))66 (37.29)59 (35.76)0.769
MMSE (mean±SEM)22.60±0.4522.59±0.490.988
MoCA (mean±SEM)18.79±0.5118.72±0.540.929
EDI (mean±SEM)12.94±0.7013.17±0.710.820
WDT (mean±SEM)18.75±1.5018.61±1.560.950
  • *Values were abnormal and clinically significant.

  • ALT, alanine aminotransferase; APTT, activated partial thromboplastic time; AST, aspartate aminotransferase; BI, Barthel Index; BUN, blood urea nitrogen; CHD, coronary heart disease; DBP, diastolic blood pressure; EDI, Executive Dysfunction Index; FBS, fasting blood sugar; GBE, Ginkgo biloba extract; MMSE, Mini-Metal State Examination; MoCA, Montreal Cognitive Assessment; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure; WDT, Webster’s digit symbol test.