Table 1

Demographic characteristics of the 381 included patients

Demographicsn (%)
Age at diagnosis (years), median (Q1–Q3)34.7 (24.3–48.6)
Age at SRS (years), median (Q1–Q3)37.5 (25.8–51.9)
 Male170 (44.6%)
 Female211 (55.4%)
Genetic mutation identified2 (0.6%)
Initial presentation
 Incidental*6 (1.6%)
 Seizure*9 (2.4%)
 Haemorrhage360 (94.5%)
 Focal neurological deficit*6 (1.6%)
Clinical symptoms pre-SRS†
 None29 (7.6%)
 Motor deficit86 (22.6%)
 Sensory deficit62 (16.3%)
 Cerebellar symptom26 (6.8%)
 Cranial nerve deficit98 (25.7%)
 Seizure77 (20.2%)
 Headaches72 (18.9%)
 Others‡56 (14.7%)
Pre-SRS seizure control (n=77)
 No seizure without medication2 (2.6%)
 No seizure with medication34 (44.2%)
 Improvement of at least 50% in frequency or intensity under medication14 (18.2%)
 Improvement of less than 50% under medication27 (35.1%)
  • *Not associated with acute or subacute haemorrhage; patients were included due to haemorrhagic events occurring in the time interval between diagnosis and radiosurgery.

  • †Patients may exhibit several symptoms pre-SRS. The percentages are calculated for each symptom per patient.

  • ‡Speech disorder, memory loss, unspecified gait trouble.

  • Q1–Q3, first to third quartiles; SRS, stereotactic radiosurgery.