Demographics | n (%) |
Age at diagnosis (years), median (Q1–Q3) | 34.7 (24.3–48.6) |
Age at SRS (years), median (Q1–Q3) | 37.5 (25.8–51.9) |
Sex | |
Male | 170 (44.6%) |
Female | 211 (55.4%) |
Genetic mutation identified | 2 (0.6%) |
Initial presentation | |
Incidental* | 6 (1.6%) |
Seizure* | 9 (2.4%) |
Haemorrhage | 360 (94.5%) |
Focal neurological deficit* | 6 (1.6%) |
Clinical symptoms pre-SRS† | |
None | 29 (7.6%) |
Motor deficit | 86 (22.6%) |
Sensory deficit | 62 (16.3%) |
Cerebellar symptom | 26 (6.8%) |
Cranial nerve deficit | 98 (25.7%) |
Seizure | 77 (20.2%) |
Headaches | 72 (18.9%) |
Others‡ | 56 (14.7%) |
Pre-SRS seizure control (n=77) | |
No seizure without medication | 2 (2.6%) |
No seizure with medication | 34 (44.2%) |
Improvement of at least 50% in frequency or intensity under medication | 14 (18.2%) |
Improvement of less than 50% under medication | 27 (35.1%) |
*Not associated with acute or subacute haemorrhage; patients were included due to haemorrhagic events occurring in the time interval between diagnosis and radiosurgery.
†Patients may exhibit several symptoms pre-SRS. The percentages are calculated for each symptom per patient.
‡Speech disorder, memory loss, unspecified gait trouble.
Q1–Q3, first to third quartiles; SRS, stereotactic radiosurgery.