Table 2

Clinical, radiological and treatment characteristics of 414 CCMs

Clinical and radiological data per CCMn (%)
Previous surgery21 (5.1%)
Location characteristics
 Adjacent to the cortex253 (61.1%)
 Adjacent to ependymal plane100 (24.2%)
Location (anatomic)
 Brainstem155 (37.4%)
 Basal ganglia and thalamus60 (14.5%)
 Supratentorial lobar area171 (41.3%)
 Cerebellum28 (6.8%)
Associated developmental venous anomaly50 (12.1%)
Number of pre-SRS haemorrhages
 1324 (78.3%)
 271 (17.1%)
 316 (3.9%)
 41 (0.2%)
 52 (0.5%)
Median (Q1–Q3) time from diagnosis to SRS, years0.9 (0.3–3.1)
Zabramski classification
 178 (19.0%)
 2307 (74.7%)
 325 (6.1%)
 41 (0.2%)
 Unknown3
Dosimetric parameter per CCM, median (Q1–Q3)
Target volume, cm3, median (Q1–Q3)0.6 (0.2–1.5)
Margin dose, Gy, median (Q1–Q3)12 (12c14)
Isocentres, median (Q1–Q3)4 (2–8)
Isodose line %, median (Q1–Q3)50 (50–51.5)
  • CCM, cerebral cavernous malformation; Q1-Q3, first to third quartiles; SRS, stereotactic radiosurgery.