Baseline characteristics of the enrolled patients in the Ginkgo biloba extract and control groups
| GBE group (n=177) | Control group (n=165) | Difference (P value) | |
| Age (years) (mean±SEM) | 64.53±0.76 | 63.27±0.83 | 0.265 |
| Women (n (%)) | 120 (67.80) | 96 (58.18) | 0.066 |
| SBP (mm Hg) (mean±SEM) | 143.09±1.54 | 145.89±1.51 | 0.196 |
| DBP (mm Hg) (mean±SEM) | 82.34±0.86 | 84.30±1.01 | 0.141 |
| Stroke history (n (%)) | 143 (80.79) | 134 (81.21) | 0.921 |
| Hypertension history (n (%)) | 108 (61) | 107 (64.8) | 0.537 |
| Diabetes mellitus history (n (%)) | 42 (23.7) | 46 (27.9) | 0.770 |
| CHD history (n (%)) | 8 (4.5) | 5 (3) | 0.518 |
| Hyperlipidaemia history (n (%)) | 7 (3.5) | 5 (3) | 0.216 |
| FBS (mmol/L) (mean±SEM) | 6.65±0.22 | 6.71±0.22 | 0.853 |
| BUN (µmol/L) (mean±SEM) | 5.23±0.13 | 7.39±1.78 | 0.224 |
| Creatinine (µmol/L)(mean±SEM) | 73.45±1.72 | 71.24±2.31 | 0.451 |
| ALT (U/L) (mean±SEM) | 18.80±0.83 | 20.90±1.09 | 0.129 |
| AST (U/L) (mean±SEM) | 19.58±0.62 | 20.43±0.81 | 0.402 |
| Triglycerides* (n (%)) | 16 (9.04) | 20 (12.12) | 0.419 |
| Thrombin time*(s) (n (%)) | 1 (0.56) | 1 (0.61) | 0.493 |
| APTT (s) (mean±SEM) | 26.60±0.51 | 25.61±0.45 | 0.162 |
| Fibrinogen (g/L) (mean±SEM) | 4.56±1.38 | 3.76±0.82 | 0.635 |
| NIHSS median (P25, P75) | 5 (4, 7) | 5 (4, 7) | 0.625 |
| BI (mean±SEM) | 60.56±1.80 | 57.79±1.85 | 0.284 |
| Independent mRS (n (%)) | 66 (37.29) | 59 (35.76) | 0.769 |
| MMSE (mean±SEM) | 22.60±0.45 | 22.59±0.49 | 0.988 |
| MoCA (mean±SEM) | 18.79±0.51 | 18.72±0.54 | 0.929 |
| EDI (mean±SEM) | 12.94±0.70 | 13.17±0.71 | 0.820 |
| WDT (mean±SEM) | 18.75±1.50 | 18.61±1.56 | 0.950 |
*Values were abnormal and clinically significant.
ALT, alanine aminotransferase; APTT, activated partial thromboplastic time; AST, aspartate aminotransferase; BI, Barthel Index; BUN, blood urea nitrogen; CHD, coronary heart disease; DBP, diastolic blood pressure; EDI, Executive Dysfunction Index; FBS, fasting blood sugar; GBE, Ginkgo biloba extract; MMSE, Mini-Metal State Examination; MoCA, Montreal Cognitive Assessment; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure; WDT, Webster’s digit symbol test.