Table 3

Associations of physical activity with radiological and clinical ICH outcomes

Physical activity
<4 hour/week
Physical activity
≥4 hour/week
OR (95% CI)P value
Midline shift,
Number/total number (%)
160/387 (41.3)65/235 (27.7)0.67 (0.44 to 0.99)*0.049
1.09 (0.64 to 1.87)†0.740
IVH,
Number/total number (%)
148/387 (38.2)55/235 (23.4)0.65 (0.42 to 0.98)*0.044
0.88 (0.55 to 1.39)†0.573
Admission NIHSS 0–4,
Number/total number (%)
102/387 (26.4)133/235 (56.6)2.53 (1.59 to 4.01)*<0.001
1.99 (1.18 to 3.35)†0.010
One-week mRS 0–3,
Number/total number (%)
75/387 (19.4)127/235 (54.0)2.12 (1.37 to 3.30)*<0.001
1.64 (1.01 to 2.66)†0.048
90-day survival,
Number/total number (%)
254/387 (65.6)217/235 (92.3)3.48 (2.06 to 5.91)*<0.001
2.91 (1.58 to 5.37)†<0.001
  • Associations of prestroke physical activity with midline shift, IVH, NIHSS 0–4, mRS 0–3 and 90-day survival were calculated in binary logistic regression models. Results were obtained from imputed data.

  • *Adjusted for haematoma location and propensity scores based on age, sex, birthland, education, income, activities of daily living, living situation, smoking, alcohol, hypertension, hyperlipidemia, prior stroke or TIA, atrial fibrillation, diabetes mellitus, cardiac disease, heart failure, dementia, cancer, lipid-lowering drugs, antiplatelet drugs, antihypertensive drugs, non-vitamin k oral anticoagulants, warfarin and International Normalised Ratio.

  • †Adjusted for haematoma location, propensity scores and haematoma volume.

  • ICH, intracerebral haemorrhage; IVH, intraventricular haemorrhage; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischaemic attack.