Multivariate logistic regression analysis for an index ischaemic stroke
| Model 1 | Model 2 | Model 3 | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| PB (per 10% increase) | 1.677 (1.381 to 2.037) | < 0.001 | 1.726 (1.411 to 2.111) | < 0.001 | 0.670 (0.467 to 0.960) | 0.029 |
| RI (per 0.1 increase) | 1.303 (1.072 to 1.584) | 0.008 | 1.312 (1.071 to 1.607) | 0.009 | 1.986 (1.529 to 2.579) | < 0.001 |
| %LRNC (per 10% increase) | 1.068 (0.837 to 1.364) | 0.596 | 1.043 (0.805 to 1.350) | 0.751 | 0.910 (0.692 to 1.196) | 0.093 |
| Complicated plaque | 1.352 (0.821 to 2.226) | 0.236 | 1.399 (0.840 to 2.329) | 0.197 | 1.598 (0.925 to 2.759) | 0.057 |
Model 1=a crude model; Model 2=adjusted for general covariates (including age, sex, hypertension, diabetes mellitus, coronary artery disease, prior stroke or transient ischaemic attack, drinking, smoking, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglyceride, homocysteine, glucose, Baseline National Institute of Health Stroke Scale and time from onset to HR-MRI); Model 3=additionally adjusted luminal stenosis.
HR-MRI, high-resolution-MRI; LRNC, lipid-rich necrotic core; PB, plaque burden; RI, remodelling index.