Table 3

Cox proportional hazards with multivariable adjustments* in all patients

Composite events (n=109)Recurrent stroke (n=74)Acute coronary syndrome (n=20)Vascular death (n=15)
HR (95% CI)P valueHR (95% CI)P valueHR (95% CI)P valueHR (95% CI)P value
No or mild vascular retinopathyReferenceReferenceReferenceReference
Moderate vascular retinopathy1.03 (0.64 to 1.67)0.9051.40 (0.76 to 2.57)0.2840.32 (0.10 to 1.03)0.0561.05 (0.31 to 3.54)0.941
Vascular retinopathy with vessel
rarefaction
1.17 (0.62 to 2.20)0.6261.47 (0.66 to 3.24)0.3460.84 (0.22 to 3.24)0.8020.51 (0.05 to 4.94)0.558
  • *Model adjusted for age, sex, BMI, ABCD2, index event type, randomisation arm, hypertension, diabetes mellitus, atrial fibrillation, current smoking, stroke aetiology and carotid surgery.

  • ABCD2, age, blood pressure, clinical findings, duration of symptoms and presence or absence of diabetes; BMI, body mass index.