Cox proportional hazards with multivariable adjustments* in all patients
Composite events (n=109) | Recurrent stroke (n=74) | Acute coronary syndrome (n=20) | Vascular death (n=15) | |||||
HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
No or mild vascular retinopathy | Reference | Reference | Reference | Reference | ||||
Moderate vascular retinopathy | 1.03 (0.64 to 1.67) | 0.905 | 1.40 (0.76 to 2.57) | 0.284 | 0.32 (0.10 to 1.03) | 0.056 | 1.05 (0.31 to 3.54) | 0.941 |
Vascular retinopathy with vessel rarefaction | 1.17 (0.62 to 2.20) | 0.626 | 1.47 (0.66 to 3.24) | 0.346 | 0.84 (0.22 to 3.24) | 0.802 | 0.51 (0.05 to 4.94) | 0.558 |
*Model adjusted for age, sex, BMI, ABCD2, index event type, randomisation arm, hypertension, diabetes mellitus, atrial fibrillation, current smoking, stroke aetiology and carotid surgery.
ABCD2, age, blood pressure, clinical findings, duration of symptoms and presence or absence of diabetes; BMI, body mass index.