Table 4

Post hoc analysis: Cox proportional hazards with multivariable adjustments in patients with diabetes mellitus and hypertension

Composite events (n=32)*Recurrent stroke (n=20)*Acute coronary syndrome (n=7)Vascular death (n=5)†
HR (95% CI)P valueHR (95% CI)P valueHR (95% CI)P valueHR (95% CI)P value
No or mild vascular retinopathyReferenceReferenceReferenceReference
Moderate vascular retinopathy0.82 (0.32 to 2.13)0.6852.56 (0.51 to 12.91)0.254002.13 (0.17 to 26.14)0.554
Vascular retinopathy with vessel rarefaction2.11 (0.47 to 9.54)0.33324.14 (2.74 to 212.50)0.004008.15 (0.25 to 262.14)0.236
  • *Model adjusted for age, sex, BMI, ABCD2, index event type, randomisation arm, atrial fibrillation, current smoking, stroke aetiology and carotid surgery.

  • †Model adjusted for age, sex, BMI, ABCD2, index event type, randomisation arm, current smoking and carotid surgery.

  • ABCD2, age, blood pressure, clinical findings, duration of symptoms and presence or absence of diabetes; BMI, body mass index.