Demographic characteristics of patients stratified by years
| 2005 (N=7494 (26.5%)) | 2010 (N=9989 (35.3%)) | 2015 (N=10 794 (38.2%)) | Ptrend | |
| Demographic | ||||
| Age, year (median, IQR) | 67.0 (57.0–74.0) | 68.0 (59.0–75.0) | 67.0 (59.0–76.0) | <0.001 |
| Women (no (weighted %, 95% CI)) | 3001 (38.7 (36.9 to 40.5)) | 4069 (40.2 (39.1 to 41.3)) | 4516 (39.8 (39.0 to 40.5)) | 0.60 |
| Cerebrovascular risk factors (no (weighted %, 95% CI)) | ||||
| Hypertension | 5310 (70.5 (68.8 to 72.2)) | 7474 (76.7 (75.8 to 77.6)) | 7961 (74.8 (74.2 to 75.5)) | 0.02 |
| Diabetes | 1466 (22.4 (20.9 to 23.9)) | 2072 (25.1 (24.1 to 26.0)) | 2545 (27.8 (27.1 to 28.5)) | <0.001 |
| Dyslipidaemia | 567 (7.4 (6.4 to 8.4)) | 1328 (14.7 (13.9 to 15.4)) | 2109 (23.3 (22.7 to 23.9)) | <0.001 |
| Atrial fibrillation | 514 (6.6 (5.7 to 7.5)) | 582 (5.1 (4.6 to 5.6)) | 696 (5.6 (5.3 to 6.0)) | 0.47 |
| Current smoker | 1024 (13.9 (12.6 to 15.1)) | 1550 (17.5 (16.7 to 18.4)) | 1581 (19.4 (18.7 to 20.0)) | <0.001 |
| Number of risk factors ≥3 | 552 (7.7 (6.7 to 8.6)) | 1479 (17.1 (16.3 to 17.9)) | 2544 (27.5 (26.8 to 28.1)) | <0.001 |
| Medical history (no (weighted %, 95% CI)) | ||||
| Stroke | 1351 (21.2 (19.7 to 22.7)) | 2166 (23.1 (22.2 to 24.1)) | 2738 (29.2 (28.5 to 29.9)) | <0.001 |
| Coronary heart disease | 1446 (21.0 (19.5 to 22.5)) | 2009 (23.6 (22.7 to 24.5)) | 2570 (27.0 (26.3 to 27.7)) | <0.001 |
| Myocardial infarction | 112 (1.6 (1.2 to 2.1)) | 131 (1.4 (1.2 to 1.7)) | 175 (1.9 (1.6 to 2.1)) | 0.07 |
| Insurance status (no (weighted %, 95% CI)) | ||||
| Urban Employee Basic Medical Insurance | 1420 (24.6 (23.0 to 26.1)) | 2254 (30.4 (29.4 to 31.4)) | 3186 (33.6 (32.9 to 34.3)) | <0.001 |
| Urban Resident Basic Medical Insurance | 0 | 811 (10.7 (10.0 to 11.4)) | 1010 (9.3 (8.9 to 9.8)) | |
| New Rural Co-operative Medical Insurance Scheme | 142 (1.6 (1.1 to 2.0)) | 2234 (18.9 (18.0 to 19.7)) | 4275 (33.4 (32.7 to 34.1)) | |
| Self-payment | 3395 (39.4 (37.6 to 41.2)) | 1583 (15.8 (15.0 to 16.6)) | 914 (8.2 (7.8 to 8.6)) | |
| Other | 2537 (34.5 (32.7 to 36.2)) | 3107 (24.1 (23.2 to 25.1)) | 1409 (15.5 (14.9 to 16.0)) | |
| Region (no (weighted %, 95% CI)) | ||||
| Rural | 3986 (25.6 (24.0 to 27.2)) | 5429 (32.0 (31.0 to 33.0)) | 5867 (34.7 (34.0 to 35.4)) | <0.001 |
| Urban | 3508 (74.4 (72.8 to 76.0)) | 4560 (68.0 (67.0 to 69.0)) | 4927 (65.3 (64.6 to 66.0)) | |
| Clinical characteristic | ||||
| Time from symptom onset to admission (days; median (IQR)) | 2.0 (0.0–5.0) | 2.0 (0.0–6.0) | 2.0 (0.0–7.0) | <0.001 |
| Time from symptom onset to admission (days; no (weighted %, 95% CI)) | ||||
| <1 | 2491 (30.7 (29.1 to 32.4)) | 2906 (27.7 (26.7 to 28.6)) | 2873 (26.4 (25.8 to 27.1)) | |
| 1–7 | 3858 (52.1 (50.3 to 53.9)) | 5259 (54.2 (53.1 to 55.3)) | 5825 (53.5 (52.7 to 54.2)) | |
| ≥8 | 1138 (17.2 (15.8 to 18.5)) | 1814 (18.2 (17.3 to 19.0)) | 2088 (20.1 (19.5 to 20.7)) | |
| Coma (no (weighted %, 95% CI)) | 214 (2.3 (1.7 to 2.8)) | 175 (1.6 (1.3 to 1.9)) | 158 (1.6 (1.4 to 1.8)) | 0.044 |
| Limb weakness (muscle power 0–4) (no (weighted %, 95% CI)) | 3089 (38.4 (36.6 to 40.2)) | 3633 (34.6 (33.6 to 35.6)) | 3391 (33.2 (32.5 to 34.0)) | <0.001 |
| Limb weakness (muscle power 0–3) (no (weighted %, 95% CI)) | 1984 (24.0 (22.4 to 25.5)) | 2179 (19.5 (18.6 to 20.3)) | 1873 (17.4 (16.9 to 18.0)) | <0.001 |
| Aphasia or dysarthria (no (weighted %, 95% CI)) | 2031 (29.0 (27.4 to 30.7)) | 2428 (28.8 (27.8 to 29.8)) | 2533 (27.3 (26.6 to 27.9)) | 0.007 |
| Systolic blood pressure (mm Hg; mean (SD)) | 150.2±16.2 | 148.3±22.1 | 145.6±28.8 | <0.001 |
| Cholesterol (mmol/L; median (IQR)) | 4.8 (4.1–5.5) | 4.7 (4.0–5.5) | 4.6 (3.8–5.3) | <0.001 |
| Low-density lipoprotein (mmol/L; median (IQR)) | 2.9 (2.3–3.4) | 2.8 (2.2–3.4) | 2.6 (2.1–3.3) | <0.001 |
| Fast glucose (mmol/L; median (IQR)) | 5.5 (4.8–6.8) | 5.5 (4.8–6.7) | 5.6 (4.9–6.9) | 0.022 |
| Uric acid (μmol/L; median (IQR)) | 291.0 (227.0–364.0) | 294.0 (237.9–363.0) | 308.2 (248.0–376.9) | <0.001 |
| Alanine transaminase (U/L; median (IQR)) | 18.5 (14.0–28.0) | 18.0 (13.0–26.0) | 18.0 (13.0–26.0) | <0.001 |
| Estimated glomerular filtration rate (mL/(min/1.73 m2)) | 83.0 (65.7–100.0) | 91.4 (72.0–104.6) | 95.4 (78.6–107.3) | <0.001 |
| ≥90 | 2000 (40.4 (38.4 to 42.4)) | 4186 (52.4 (51.3 to 53.6)) | 5557 (60.4 (59.6 to 61.2)) | <0.001 |
| <90 | 3386 (59.6 (57.6 to 61.6)) | 4392 (47.6 (46.4 to 48.7)) | 4087 (39.6 (38.8 to 40.4)) | <0.001 |
Data are presented by weighted mean along with SD (mean±SD) or median along with IQR (median (IQR)) for continuous variables, and unweighted frequency along with weighted % (95% CI) for categorical variables.