Secondary outcome variables
| Characteristics | IA thrombolytics (n=95) | No IA thrombolytics (n=2168) | OR | 95% CI | aOR* | 95% CI |
| Favourable functional outcome, n (%)† | 43/88 (48.9) | 897/2018 (44.4) | 1.18 | 0.78 to 1.80 | 1.16 | 0.71 to 1.90 |
| Successful reperfusion, n (%)‡ | 45/92 (48.9) | 1429/2120 (67.4) | 0.46 | 0.30 to 0.70 | 0.57 | 0.36 to 0.90 |
| Excellent reperfusion, n (%)§ | 29/92 (31.5) | 992/2120 (46.8) | 0.54 | 0.35 to 0.85 | 0.68 | 0.43 to 1.09 |
| Early neurological recovery, n (%)¶ | 6/91 (6.6) | 153/1962 (7.8) | 0.83 | 0.36 to 1.93 | 0.96 | 0.40 to 2.29 |
| Symptomatic intracranial haemorrhage, n (%)** | 5/95 (5.3) | 129/2168 (6.0) | 0.88 | 0.35 to 2.20 | 0.82 | 0.32 to 2.10 |
*Results were adjusted for age, a medical history of atrial fibrillation and previous stroke, use of anticoagulation, National Institutes of Health Stroke Scale score at baseline, collateral score, intravenous thrombolysis, procedural use of heparin and time from groin puncture to recanalisation or last contrast bolus.
†Favourable functional outcome was defined as an modified Rankin Scale score of ≤2 at 90 days after EVT.
‡Successful reperfusion was defined as extended Thrombolysis In Cerebral Infarction score of ≥2B.
§Excellent reperfusion was defined as extended Thrombolysis In Cerebral Infarction score of ≥2C.
¶Early neurological recovery was defined as National Institutes of Health Stroke Scale score of 0 or 1 within 24 hours postprocedural, or a decrease of 8 points relative to baseline.
**An intracranial haemorrhage was considered to be symptomatic if patients deteriorated neurologically (a decline of at least four points on the National Institutes of Health Stroke Scale) or died within 90 days after endovascular thrombectomy and the haemorrhage was related to the clinical deterioration (according to the Heidelberg criteria).
aOR, adjusted OR; IA, intra-arterial; n, number.