Comparison of risk factors among single LICH groups
| CAA pattern (n=93) | HTN-cSVD pattern (n=53) | Mixed NHIM (n=19) | No NHIM (n=96) | |
| Age (years), mean±SD | 72.5±10.6 | 78.7±10.3* | 80.4±8.9† | 68.1±13.7‡ |
| Female sex | 49 (53) | 31 (59) | 14 (74) | 53 (55) |
| Hypertension | 71 (76) | 40 (76) | 17 (90) | 65 (68) |
| Hyperlipiaemia | 47 (51) | 30 (57) | 7 (37) | 47 (49) |
| Diabetes | 13 (14) | 9 (17) | 3 (16) | 15 (16) |
| Coronary disease | 12 (13) | 11 (21) | 2 (11) | 13 (14) |
| Atrial fibrillation | 18 (19) | 11 (21) | 4 (21) | 10 (10) |
| SCr (mg/dL), mean±SD | 0.96±0.25 | 1.00±0.32 | 0.99±0.33 | 0.97±0.63 |
| LVH | 17 (20)§ | 25 (50)¶ | 7 (39)** | 10 (12)†† |
The table above shows the patient demographics, frequency of vascular risk factors, and markers of HTN-cSVD (SCr and LVH) among the various subgroups of single LICH. Data are counts (n) and percentages (%) unless specified otherwise. Of note, p<0.05 when * is compared with ‡, † is compared with ‡, § is compared with ¶, ¶ is compared with ** and ** is compared with ††.
CAA, cerebral amyloid angiopathy; HTN-cSVD, hypertensive cerebral small vessel disease; LICH, lobar intracerebral haemorrhage; LVH, left ventricular hypertrophy; NHIM, non-haemorrhagic imaging markers; SCr, serum creatinine; SCr, serum creatinine.