Characteristics | IA thrombolytics (n=95) | No IA thrombolytics (n=2168) | P value |
Thrombectomy technique, n (%)* | |||
Stent retriever | 61/95 (64.2) | 1647/2168 (76.0) | 0.01 |
Aspiration | 21/95 (22.1) | 884/2168 (40.8) | <0.001 |
Other | 9/95 (9.5) | 141/2168 (6.5) | 0.26 |
Total revascularisation attempts, n (%) | |||
1 | 19/67 (28.4) | 803/1994 (40.3) | 0.09 |
2 | 24/67 (35.8) | 470/1994 (23.6) | |
3 | 10/67 (14.9) | 316/1994 (15.8) | |
≥4 | 14/67 (20.9) | 405/1994 (20.3) | |
IA thrombolytics, n (%) | |||
Urokinase† | 63/95 (66.3) | N/A | |
Alteplase‡ | 32/95 (33.7) | N/A | |
IA thrombolytics attempt, n (%) | |||
Primary attempt | 26/91 (28.6) | N/A | |
Adjuvant attempt | 65/91 (71.4) | N/A | |
Location occlusion IA thrombolytics, n (%) | |||
Proximal occlusion | 67/88 (76.1) | N/A | |
Distal occlusion | 21/88 (23.9) | N/A | |
General anaesthesia, n (%) | 32/90 (35.6) | 562/2091 (26.9) | 0.07 |
Time from stroke onset to groin puncture, median (IQR), minutes | 200 (154–250) | 190 (150–245) | 0.37 |
Time from groin puncture to recanalisation or last contrast bolus, median (IQR), minutes | 72 (58–108) | 60 (40–85) | <0.001 |
*Sum may be less than 100% due to administration of IA thrombolytics only, or exceed 100% due to a combination of treatment techniques.
†Median dose was 250 000 IU (IQR, 1 93 750–2 50 000).
‡Median dose was 20 mg (IQR, 12–20).
IA, intra-arterial; n, number; N/A, not applicable.