Table 2

Outcomes compared across three antihypertensive groups

OutcomeHydralazineLabetalolNicardipineP value
SBP change, mm Hg, median (Q1, Q3)−13 (−34, 0)−18 (−36 to –5)−19.5 (−41,–3)0.353
DBP change, mm Hg, Median (Q1, Q3)−9 (−25, 0)−9 (−20, 0)−12.5 (−27, 0) 0.002
HE, mL, median (Q1, Q3)0.15 (−0.32, 2.83)0.04 (−0.88, 1.37)0.05 (−0.89, 1.55)0.552
6 month mortality, n (%)9 (13.9)81 (22.7)149 (26.4)0.056
Length of stay, days, median (Q1, Q3)8 (5, 16)8 (4, 17.5)10 (6, 18) 0.004
Discharge mRS=0–3, n (%)28 (41.8)153 (40.7)210 (36.3)0.322
90-day mRS=0–3, n (%)34 (58.6)186 (65.3)272 (61.7)0.494
6 month mRS=0–3, n (%)35 (62.5)200 (71.5)272 (65.5)0.109
12 month mRS=0–3, n (%)33 (70.2)183 (73.2)262 (67.4)0.291
Discharge to facility, n (%)13 (21.3)68 (18.8)141 (25.4)0.068
  • P value: Kruskal-Wallis test for continuous variables, χ2 test for categorical variables with significance set at <0.05. Discharge to facility defined as discharge to skilled nursing home, assisted living, outside hospital or acute care setting.

  • DBP, diastolic blood pressure; HE, haematoma expansion; mRS, modified Rankin Scale; Q1, lower quartile; Q3, upper quartile; SBP, systolic blood pressure.