Clinical characteristics of the patients harbouring GGC repeat expansion in NOTCH2NLC
| Patient | Sex | Age at onset | Repeat number | Initial symptoms | Duration | Cerebrovascular accident | Muscle weakness | Sensory disturbance | ||
| Stroke | Risk factors | Family history/stroke | ||||||||
| 1 | M | 62 | 98 | Dizziness | 1 Year | – | HHcy | – | – | – |
| 2 | F | 66 | 92 | Dizziness | 1 Year | CI, ICH | HTN | – | – | – |
| 3 | F | 64 | 65 | Dizziness | 10 Years | – | HTN, HL | + | – | – |
| 4 | M | 62 | 57 | Weakness of the limb | 2 Months | CI | HL, DM | – | + | + |
| 5 | M | 37 | 50 | Speech impairment | 2 Months | CI | HTN, HHcy | + | – | – |
| 6 | F | 48 | 46 | Dizziness, Headache | 10 Days | – | HTN | – | – | – |
| 7 | M | 63 | 43 | Speech impairment | 4 Months | CI | – | – | + | – |
| 8 | F | 67 | 42 | Speech impairment, Weakness of the limb | 5 Months | CI | HTN, HHcy, CAD | – | + | – |
| 9 | M | 65 | 41 | Dizziness | 6 Days | – | HTN, HHcy | – | ||
‘–’ indicates absent and ‘+’ indicates present.
CAD, coronary artery disease; CI, cerebral infarction; DM, diabetes mellitus; F, female; HHcy, hyperhomocysteinaemia; HL, hyperlipaemia; HTN, hypertension; ICH, intracerebral haemorrhage; M, male.;