Proportion of patients with functional dependence stratified by ADVISING score
| 90-day functional dependence after ICH | ||
| Training cohort (n=2111) | Validation cohort (n=733) | |
| C-statistic (95% CI) | 0.866 (0.850 to 0.881) | 0.884 (0.861 to 0.908) |
| Score | ||
| 0 | 3/23 (13.0) | 0/4 (0) |
| 1 | 7/132 (5.3) | 2/39 (5.1) |
| 2 | 25/222 (11.3) | 5/59 (8.5) |
| 3 | 83/377 (22.0) | 26/121 (21.5) |
| 4 | 177/396 (44.7) | 76/149 (51.0) |
| 5 | 215/363 (59.2) | 96/139 (69.1) |
| 6 | 207/255 (81.2) | 67/87 (77.0) |
| 7 | 156/176 (88.6) | 55/60 (91.7) |
| 8 | 103/106 (97.2) | 43/43 (100.0) |
| 9 | 38/38 (100.0) | 25/25 (100.0) |
| 10 | 20/20 (100.0) | 7/7 (100.0) |
| 11 | 2/2 (100.0) | – |
| 12 | 1/1 (100.0) | – |
| Dichotomised score | ||
| 0–4 | 295/1150 (25.7) | 109/372 (29.3) |
| 5–12 | 742/961 (77.2) | 293/361 (81.2) |
| Dichotomised test characteristics (95% CI) | ||
| Sensitivity | 0.716 (0.687 to 0.743) | 0.729 (0.682 to 0.771) |
| Specificity | 0.796 (0.770 to 0.820) | 0.795 (0.746 to 0.836) |
| PPV | 0.772 (0.744 to 0.798) | 0.812 (0.767 to 0.850) |
| NPV | 0.743 (0.717 to 0.768) | 0.707 (0.657 to 0.752) |
| PLR | 3.509 (3.099 to 3.973) | 3.548 (2.847 to 4.421) |
| NLR | 0.357 (0.324 to 0.394) | 0.341 (0.290 to 0.401) |
The proportion of patients was represented as n/N (%).
ICH, intracerebral haemorrhage; NLR, negative likelihood ratio; NPV, negative predictive value; PLR, positive likelihood ratio; PPV, positive predictive value.