Univariate and multivariate analyses for the primary and secondary outcomes
| Variable, n (%) | DEVT (n=241) | IVT+EVT (n=69) | OR | P value | aOR* | P value* |
| Primary outcome | ||||||
| mRS 0–2 at 90 days | 63 (26.14) | 29 (42.03) | 0.49 (0.28 to 0.85) | 0.01 | 0.46 (0.24 to 0.85) | 0.01 |
| Secondary outcome | ||||||
| Mortality at 90 days | 63 (26.14) | 13 (18.84) | 1.52 (0.78 to 2.97) | 0.21 | 1.79 (0.87 to 3.71) | 0.11 |
| Occlusion at 24 hours | 58 (24.07) | 11 (15.94) | 1.67 (0.82 to 3.40) | 0.16 | 1.38 (0.68 to 2.79) | 0.37 |
| mTICI ≥2b post-EVT | 181 (75.10) | 47 (68.12) | 1.41 (0.79 to 2.53) | 0.25 | 1.50 (0.82 to 2.77) | 0.19 |
| Any ICH | 50 (20.75) | 12 (17.39) | 1.24 (0.62 to 2.49) | 0.54 | 1.18 (0.58 to 2.39) | 0.65 |
| sICH | 21 (8.71) | 5 (7.25) | 1.22 (0.44 to 3.36) | 0.70 | 1.17 (0.41 to 3.30) | 0.77 |
P value for comparison between patients treated with DEVT and bridging treatment.
*Adjusted for age, baseline NIHSS score, prestroke mRS score, history of stroke/TIA and onset to puncture.
aOR, adjusted OR; DEVT, direct endovascular treatment; EVT, endovascular treatment; ICH, intracranial haemorrhage; IVT, intravenous thrombolysis; mRS, modified Rankin Scale; mTICI, modified Thrombolysis in Cerebral Infarction Score; NIHSS, National Institutes of Health Stroke Scale; sICH, symptomatic intracranial haemorrhage; TIA, transient ischaemic attack.