Table 3

Multivariable logistic regression models predicting an abnormal TTE finding (left), a Category I finding (left-centre), a Category II finding (right-centre) and a Category III finding (right) among those with no prestroke history of heart failure

Covariates	TTE abnormality n=4157 OR (95% CI)	P value	Model c-statistic	Category I abnormality n=981 OR (95% CI)	P value	Model c-statistic	Category II abnormality n=1519 OR (95% CI)	P value	Model c-statistic	Category III abnormality n=3535 OR (95% CI)	P value	Model c- statistic
Older age	2.01 (1.73 to 2.34)	<0.001	0.71	0.53 (0.45 to 0.62)	<0.001	0.68	1.74 (1.50 to 2.01)	<0.001	0.73	2.83 (2.48 to 3.24)	<0.001	0.75
Male gender										1.22 (1.07 to 1.39)	0.004
Caucasian				1.36 (1.10 to 1.70)	0.005
Coronary artery disease/prior MI	3.44 (2.64 to 4.47)	<0.001					3.73 (3.21 to 4.34)	<0.001		2.02 (1.66 to 2.45)	<0.001
Atrial fibrillation	3.15 (2.40 to 4.14)	<0.001		0.61 (0.48 to 0.77)	<0.001		1.75 (1.49 to 2.05)	<0.001		3.41 (2.71 to 4.29)	<0.001
Prior antihypertensive medication	1.32 (1.14 to 1.54)	<0.001		0.67 (0.57 to 0.79)	<0.001		1.22 (1.05 to 1.42)	0.009		1.84 (1.60 to 2.11)	<0.001
Diabetes mellitus	1.28 (1.06 to 1.54)	0.010		0.76 (0.63 to 0.93)	0.007					1.45 (1.23 to 1.71)	<0.001
Chronic kidney disease										1.62 (1.02 to 2.58)	0.041
Prior antiplatelet use				0.74 (0.62 to 0.89)	0.002
Admission NIHSS ≥4				0.63 (0.54 to 0.73)	<0.001		1.44 (1.26 to 1.65)	<0.001		1.17 (1.03 to 1.33)	0.017
Cortical infarct							1.38 (1.18 to 1.61)	<0.001
Infratentorial infarct				0.81 (0.68 to 0.96)	0.0139
Patent intracranial and extracranial arteries	1.18 (1.01 to 1.38)	0.043		1.50 (1.26 to 1.78)	<0.001		1.29 (1.12 to 1.49)	<0.001

MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; TTE, transthoracic echocardiography.