Table 3

Multivariable logistic regression models predicting an abnormal TTE finding (left), a Category I finding (left-centre), a Category II finding (right-centre) and a Category III finding (right) among those with no prestroke history of heart failure

CovariatesTTE abnormality
n=4157
OR (95% CI)
P valueModel c-statisticCategory I abnormality
n=981
OR (95% CI)
P valueModel c-statisticCategory II abnormality
n=1519
OR (95% CI)
P valueModel c-statisticCategory III abnormality
n=3535
OR (95% CI)
P valueModel
c-
statistic
Older age2.01 (1.73 to 2.34)<0.0010.710.53 (0.45 to 0.62)<0.0010.681.74 (1.50 to 2.01)<0.0010.732.83 (2.48 to 3.24)<0.0010.75
Male gender1.22 (1.07 to 1.39)0.004
Caucasian1.36 (1.10 to 1.70)0.005
Coronary artery disease/prior MI3.44 (2.64 to 4.47)<0.0013.73 (3.21 to 4.34)<0.0012.02 (1.66 to 2.45)<0.001
Atrial fibrillation3.15 (2.40 to 4.14)<0.0010.61 (0.48 to 0.77)<0.0011.75 (1.49 to 2.05)<0.0013.41 (2.71 to 4.29)<0.001
Prior antihypertensive medication1.32 (1.14 to 1.54)<0.0010.67 (0.57 to 0.79)<0.0011.22 (1.05 to 1.42)0.0091.84 (1.60 to 2.11)<0.001
Diabetes mellitus1.28 (1.06 to 1.54)0.0100.76 (0.63 to 0.93)0.0071.45 (1.23 to 1.71)<0.001
Chronic kidney disease1.62 (1.02 to 2.58)0.041
Prior antiplatelet use0.74 (0.62 to 0.89)0.002
Admission NIHSS ≥40.63 (0.54 to 0.73)<0.0011.44 (1.26 to 1.65)<0.0011.17 (1.03 to 1.33)0.017
Cortical infarct1.38 (1.18 to 1.61)<0.001
Infratentorial infarct0.81 (0.68 to 0.96)0.0139
Patent intracranial and extracranial arteries1.18 (1.01 to 1.38)0.0431.50 (1.26 to 1.78)<0.0011.29 (1.12 to 1.49)<0.001
  • MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; TTE, transthoracic echocardiography.