Demographic and clinical characteristics of subjects included to the analysis
| Patients included to the analysis | ANTIQUE patients died prior to the final visit | ANTIQUE patients excluded due to other reason | ||
| No of subjects; n (%) | 1391 | 119 | 81 | |
| Plaque thicknesson the left side; mean±SD | 2.955±1.090 | 3.625±1.126 | 3.760±1.327 | |
| Plaque thicknesson the right side; mean±SD | 2.987±1.470 | 3.577±1.107 | 3.634±1.269 | |
| Age (years); mean±SD | 68.5±10.3 | 76.1±7.2 | 70.1±9.7 | |
| Male sex; n (%) | 466 (33.5) | 77 (64.7) | 40 (49.4) | |
| Weight (kg); mean±SD | 80.5±14.7 | 82.8±15.9 | 82.9±14.4 | |
| Height (cm); mean±SD | 168.1±9.1 | 168.6±9.6 | 170.7±10.5 | |
| Body mass index; mean±SD | 28.4±4.4 | 29.1±4.9 | 28.4±4.2 | |
| Systolic blood pressure (mm Hg); mean±SD | 134.4±12.4 | 134.9±12.0 | 132.9±12.4 | |
| Diastolic blood pressure (mm Hg); mean±SD | 79.8±8.8 | 80.6±7.5 | 80.2±8.8 | |
| Arterial hypertension; n (%) | 1091 (78.4) | 95 (79.8) | 66 (81.5) | |
| Diabetes mellitus; n (%) | 299 (21.5) | 27 (22.7) | 15 (18.5) | |
| Hyperlipidaemia; n (%) | 754 (54.2) | 61 (51.3) | 40 (49.4) | |
| Coronary heart disease; n (%) | 355 (25.5) | 30 (25.2) | 25 (30.9) | |
| Atrial fibrillation; n (%) | 165 (11.9) | 13 (10.9) | 15 (18.5) | |
| History of myocardial infarction; n (%) | 131 (9.4) | 10 (8.4) | 8 (9.9) | |
| History of stroke; n (%) | 279 (20.1) | 24 (20.2) | 25 (30.9) | |
| History of vascular surgery/stenting; n (%) | 218 (15.7) | 12 (10.1) | 17 (21.0) | |
| Smoking; n (%) | 183 (13.2) | 11 (9.2) | 9 (11.1) | |
| Alcohol consumption (IU/day); n (%) | 1 | 598 (43.0) | 53 (44.5) | 25 (30.9) |
| 2 | 526 (37.8) | 32 (26.9) | 38 (46.9) | |
| 2 | 249 (17.9) | 31 (26.1) | 17 (21.0) | |
| 3 and more | 22 (1.6) | 3 (2.5) | 1 (1.2) | |
The intraobserver reliability of plaque thickness measurement was ICC=0.996, while the interobserver reliability was ICC=0.973. The measurement error σ=0.2 mm.
ANTIQUE, Atherosclerotic Plaque Characteristics Associated with a Progression Rate of the Plaque and a Risk of Stroke in Patients with the Carotid Bifurcation Plaque Study; ICC, interclass correlation coefficient; IU, international unit; n, number.