Assessment of discordance among selected variables from the Paul Coverdell National Acute Stroke Program (PCNASP) and claims data among linked patients
| PCNASP-based variables (n=5644) | Claims-based variables (n=5644) | McNemar’s test p value | Absolute difference | |
| Comorbidities*, N (%) | ||||
| Hypertension | 4021 (71.5) | 3866 (68.5) | 0.00 | 3.0 |
| Diabetes mellitus | 1780 (31.8) | 1974 (35.0) | 0.00 | 3.2 |
| Dyslipidaemia | 2590 (46.1) | 2710 (48.0) | 0.01 | 1.9 |
| Prior ischaemic stroke | 1075 (21.9) | 1192 (21.1) | 0.12 | 0.8 |
| Prior transient ischaemic attack | 406 (8.1) | 526 (9.3) | 0.08 | 1.2 |
| History of atrial fibrillation | 1155 (20.5) | 820 (14.5) | 0.00 | 6.0 |
| Carotid stenosis | 222 (4.0) | 411 (7.3) | 0.00 | 3.3 |
| Ischaemic heart disease | 1323 (23.6) | 1341 (23.8) | 0.70 | 0.2 |
| Peripheral vascular disease | 315 (5.6) | 497 (8.8) | 0.00 | 3.2 |
| Congestive heart failure | 449 (8.0) | 786 (13.9) | 0.00 | 5.9 |
| Chronic kidney disease | 138 (11.4) | 699 (12.4) | 0.00 | 1.0 |
| Obesity | 624 (39.6) | 811 (14.4) | 0.00 | 25.2 |
| Smoking | 1024 (18.3) | 455 (8.1) | 0.00 | 10.2 |
| Drug or alcohol abuse | 32 (2.8) | 61 (1.1) | 1.00 | 1.7 |
| Depression | 174 (5.6) | 556 (9.9) | 0.00 | 4.3 |
| Stroke severity and functional information at discharge† | ||||
| NIH Stroke Scale | ||||
| Mean (SD) | 6.2 (7.2) | N/A | N/A | N/A |
| Median (IQR) | 3 (1–8) | N/A | N/A | N/A |
| Ambulatory status at discharge | ||||
| Able to ambulate independently with or without device, N (%) | 2698 (50.4) | N/A | N/A | N/A |
*Comorbidities in the PCNASP are based on recorded medical history during stroke hospitalisation; comorbidities for in claims are based on International Classification of Diseases, Ninth Revision diagnoses recorded during the 183-day period prior to the stroke hospitalisation. Comorbidities in the PCNASP were characterised by varying level of missingness: information on prior ischaemic stroke, transient ischaemic attack, obesity, chronic kidney disease, drug or alcohol abuse, and depression was missing for 13.0%, 11.6%, 72.1%, 78.6%, 79.6% and 44.7%, respectively; information on the other comorbidities was missing for <1%.
†Information on National Institutes of Health (NIH) Stroke Scale and Ambulatory status at discharge was missing for 28.9% and 5.2% patients, respectively.
N/A, not applicable.